IN01001 - CAS 501364-82-5
Catalog number:
501364-82-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H25N3O4S
Molecular Weight:
439.53
COA:
Inquire
Targets:
PARP
Description:
INO1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. It inhibits PARP and results in inhibition of tumor cell DNA repair mechanisms. It has tumor cell resistance and may be used to chemotherapy and radiation therapy.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
N-(3-morpholin-4-ylpropyl)-5-oxo-6,11-dihydroindeno[1,2-c]isoquinoline-9-sulfonamide;INO-1001;5H-Indeno[1,2-c]isoquinoline-9-sulfonaMide, 6,11-dihydro-N-[3-(4-Morpholinyl)propyl]-5-oxo
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
INO1001 has tumor cell resistance and may be used to chemotherapy and radiation therapy.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Density:
1.42±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
LTZVLHHIAUKGBP-UHFFFAOYSA-N
InChI:
InChI=1S/C23H25N3O4S/c27-23-20-5-2-1-4-19(20)21-15-16-14-17(6-7-18(16)22(21)25-23)31(28,29)24-8-3-9-26-10-12-30-13-11-26/h1-2,4-7,14,24H,3,8-13,15H2,(H,25,27)
Canonical SMILES:
C1COCCN1CCCNS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3)C5=CC=CC=C5C(=O)N4
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