|Targets||Others (Nonspecific immune stimulation)|
Low-dose preferentially deplets Treg cells; An alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities; Phase I–II
Recombinant human IFNα; A type I interferon consisting of 165 amino acid residues with lysine in position 23. It is used extensively as an antiviral or antineop...
Recombinant human IL‑2; Interleukin-2 is a secreted cytokine, also called IL-2. Aldesleukin (IL-2 made in the laboratory) is being used as a biological response...
Recombinant IL‑2–diphtheria toxin conjugate; It works by interfering with the growth of cancer cells, which results in the death of the cells; Phase I–II
Anti-CD25 (IL-2 receptor α‑chain) antibody; A humanized mAb of the human IgG1 isotype that binds specifically to the Tac epitope on the α-subunit (CD25) of the ...