Idoxuridine - CAS 54-42-2
Catalog number: 54-42-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C9H11IN2O5
Molecular Weight:
354.1
COA:
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Targets:
HSV
Description:
It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing.Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM
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Purity:
>98%
Synonyms:
NSC 39661, SKF 14287
MSDS:
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1.A systematic review and meta-analysis to compare the efficacy of acyclovir 3% ophthalmic ointment to idoxuridine in curing herpetic keratitis by Day 7 of treatment.
Balderson DE1, Cai G2, Fries MA3, Kleinman DM4, McLaughlin MM5, Trivedi TM6, Wurzelmann JI7, Young SB8. BMC Ophthalmol. 2015 Apr 17;15:42. doi: 10.1186/s12886-015-0022-2.
BACKGROUND: This objective of the review and analysis is to demonstrate that acyclovir (ACV) 3% ophthalmic ointment is superior to idoxuridine (IDU) in treating herpetic keratitis (HK) presenting as dendritic and geographic ulcer sub-types.
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CAS 54-42-2 Idoxuridine

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