IDE-2 - CAS 1136466-93-7
Catalog number:
1136466-93-7
Category:
Stem Cell Molecule
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C12H20N2O3
Molecular Weight:
240.3
COA:
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Description:
IDE-2 was identified in a high throughput screen as an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells. IDE-2 is able to generate Sox17+/FoxA2+ cells to an equal or greater efficiency than that of protein (i.e. Activin A or Nodal) IDEs in mouse or human ES cell cultures. It functions in part via activation of TGF-β signaling, as evident by Smad2 phosphorylation. IDE-2 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.
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Purity:
0.98
Appearance:
White Powder
MSDS:
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Application:
Differentiation
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CAS 1136466-93-7 IDE-2

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