|Description||Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures.|
|Synonyms||AG 3-5; 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one; 3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone;|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||Both heat sensitive (VR1) and cold-sensitive (CMR1 (rat); TRPM8 (human)) receptors|
|Quality Standard||Enterprise Standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
|Current Developer||Tufts University|
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