ICA-121431 - CAS 313254-51-2
Catalog number:
313254-51-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H19N3O3S2
Molecular Weight:
449.54
COA:
Inquire
Targets:
Sodium Channel
Description:
ICA-121431 is a potent and selective inhibitor of human NaV1.3 (IC50=13 nM) and NaV1.1 channels (IC50=23 nM) with 1,000 fold selectivity against other resistant sodium channels like human Nav1.5 or Nav1.7 channels.
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Appearance:
Solid powder
Synonyms:
2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide 2,2-diphenyl-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)acetamide ICA-121431
Solubility:
Soluble to ≥ 44 mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -77℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Density:
1.409±0.06 g/cm3
InChIKey:
URSQNPPONHUJDL-UHFFFAOYSA-N
InChI:
1S/C23H19N3O3S2/c27-22(21(17-7-3-1-4-8-17)18-9-5-2-6-10-18)25-19-11-13-20(14-12-19)31(28,29)26-23-24-15-16-30-23/h1-16,21H,(H,24,26)(H,25,27)
Canonical SMILES:
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4
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