|Description||Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potentia|
Verapamil HCl is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent.
PD0176078 is a novel N-type calcium channel blocker.
Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxi...
Elpetrigine, also known as GW 273293 and JZP-4, has a blocking effect on calcium channels and potassium channels which has been in clinical bipolar disorders an...
NP-118809 is a N-type calcium channel blocker exhibits both anti-allodynic and anti-hyperalgesic activity in the spinal nerve ligation model of neuropathic pain...
ω-Agatoxin TK is a kind of toxin found in the venom of the funnel web spider. It is a selective and potent blocker of CaV2.1 P-type and Q-type calcium channels....
Dopropidil, also called as ORG 30701, is a cardioactive drug to be classified as a calcium antagonist with combined class I and class VI antiarrhythmic properti...
UK-1745, an indole derivative, has been found to be a Calcium channel antagonist that was once studied in the treatment of arrhythmias as well as heart failure.
trans-Ned 19, a structural analog of NAADP, is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist.trans-Ned 19 inhibits NAADP-mediated Ca2+ rele...
Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and r...
R 568 hydrochloride
R 568 is positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR), increasing the sensitivity to activation by extrace...
CGS 9343B is a calmodulin (CaM) antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity (an IC50 = 3.3 nM). It also prevents estrogen-ind...
Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.It is used in the treatment of primary (essential) hypertension to decrease bloo...
L-651,582 is a novel inhibitor of both cAMP-phosphodiesterases and GMP-phosphodiesterases. It is also an orally active calcium channel blocker. It prevents oxid...
Flunarizine is a selective calcium entry blocker, which has calmodulin binding properties and histamine H1 blocking activity. It may help to reduce the severity...
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
CALP1 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site and activating phosphodiesterase. CALP1 also binds to cytoplasmic si...
SR 33805 oxalate
SR 33805 oxalate is a potent Ca2+ channel antagonist that binds allosterically to the a1-subunit of L-type Ca2+ channels (Kd = 20 pM). SR 33805 displays selecti...
Ned K, a NAADP inhibitor, prevents Ca2+ oscillations in rat cardiomyocytes in vitro during simulated ischemia and reperfusion, but exhibits no significant effec...
Amlodipine maleate is a long-acting dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker). It inhibits the movement of calcium ion...