|Description||Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.|
Ezetimibe produces a significant reduction in total cholesterol, LDL cholesterol, and triglycerides as well as a small but significant increase in HDL cholester...
Sodium formononetin-3'-sulfonate is a water-sol. derivate of formononetin. It has a protective potential against myocardial infarction injury. It not only had f...
LY 249933 is a bio-active molecular under the development of Eli Lilly. It has positive inotropic activity as a cardioselective 1,4-dihydropyridine compound.
Dicloralurea, a veterinary food additive, could restrain the formation of methane in herbicide ruminants for behaving as a growth stimulant.
Docosatrienoic acid is a rare ω-3 fatty acid, not readily detected in normal phospholipid PUFA pools. Docosatrienoic acid inhibits LTB4 binding to pig neutrophi...
FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy.
Carbinoxamine is a antihistamine and anticholinergic agent used in the treatment of severe itching in patients with CD5.
PrP (106-126), a peptide corresponding to the prion protein (PrP) amyloidogenic region, interacted selectively with PBEC via their luminal side, and caused cumu...
Natural demethoxy curcuminoid. Anticancer, antiproliferative and antioxidant activity. Inhibits various signaling pathways including Wnt/β-catenin, AMPK and MAP...
TC-T 6000 is a potent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM), displaying 20-fold and 80-fold selectivity for ENT4 over ENT2 an...
SB 747651A tetrahydrochloride is a potent and ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1) with an IC50 value of 11 nM.
FK866 is a nicotinamide phosphoribosyltransferase (NMPRTase) inhibitor with potential antineoplastic and antiangiogenic activity. FK866 inhibits the biosynthesi...
Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.
Interferes with TLR4, TLR2/6 signaling; Orally active immunomodulatory agent; Inhibits TNF-α secretion via interference of macrophage TLR4 and TLR 2/6 signaling...
(±)-Propionylcarnitine chloride is the homolog of acetylcarnitine chloride, which is used in the synthetic preparation of pure esters of dl-carnitine chloride w...
Fasentin is a GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Fasentin sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) via regulating the extrin...
TDFA is a protein arginine deiminase 4 (PAD4) inhibitor (IC50 = 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively) used for the treatment of au...
The hydrochloride salt form of Oxyphencyclimine which could influence the peripheral parasympathetic system and increase the stomach secretions.
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezi...
NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease.