|Description||Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.|
PXS 4728A is a VAP-1 (aka SSAO/AOC3) inhibitor with IC50 values 5 nM in the clinical trial for the treatment of non-alcoholic steatohepatitis (NASH). Studies sh...
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases.
XE 991 is a KCNQ channel and M-current blocker potentially for the treatment of AD.
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity o...
Phosalone can be used as insecticide and acaricide.
ARV-825, a BRD4 inhibitor, has extensive anti-AML activity and modulates tumor microenvironment and metabolism to overcome stromamediated drug resistance. DC50...
Hydralazine HCl is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.
Alibendol is an antispasmodic,choleretic, and cholekinetic.
Norelgestromin is a metabolite of Norgestimate which is a steroidal progestin.
AT 1902 is a bio-active compound, but no detailed information has been published yet.
J 147, under the IUPAC name N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide, a phenyl hydrazide compound that has been...
Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
1-methyl-7-nitroisatoic anhydride is a reagent which could detect local nucleotide flexibility. It is the most useful reagents for probing 2-hydroxyl reactivity...
Tirasemtiv is a a small-molecule fast-skeletal-troponin activator, which is being developed as a potential treatment for diseases and conditions associated with...
Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver...
Kaempferide is an O-methylated flavonol. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L...
Crustacean Cardioactive Peptide (CCAP), originally identified in the pericardial organs of the shore crab, Carcinus means, is a highly conserved, amidated cycli...
ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...
Tuftsin diacetate is a macrophage/microglial activator.
Epithalon is a synthetic tetra-peptide used to regulate the cell cycle through up-regulation of telomerase activity showing anticancer and anti-tumor metastati...