|Description||Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner.|
2-Ethylhexyl salicylate could be commonly used in cosmetics and sunscreens acting as a skin penetration enhancer and could absorb UVB rays at some extent.
CFLZ-567 is a key intermediate for making carfilzomib. carfilzomib is a selective proteasome inhibitor as an anti-cancer drug.
Choline Fenofibrate is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipide...
Verbascoside is a bioactive polyphenol from olive oil mill wastewater with known antioxidant activity, which is a protein kinase C inhibitor.
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the...
ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...
Melphalan flufenamide, is a melphalan prodrug in which the alkylating agent melphalan is bound to flufenamide, alkylates DNA at the N7 position of guanine resid...
Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topo...
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
LY 189332 is a bio-active molecular under the development of Eli Lilly as an antimetastatic drug.
Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities.
Metixene is an anticholinergic used as an antiparkinsonian agent for the symptomatic treatment of parkinsonism.
Cgp 15425 is a bio-active chemical,but no detailed information has been published yet.
Ornipressin Acetate, an analogue of Vasopressin, is used as a vasoconstrict or haemostatic and renal agent.
LY 140091 is a bio-active chemical, but no detailed information has been published yet.
Setmelanotide is a melanocortin 4 receptor (MC4R) agonist (EC50= 0.27 nM for human MC4R) that is used as a peptide drug and investigational anti-obesity medicat...
Tubeimoside II is a natural analogue of oleanane type of triterpenoid saponin, showing anti-inflammatory, antitumor, and antitumor-promoting effects.
Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancrea α cells.
Isopropamide is a long-acting anticholinergic drug. It can be used for the treatment of peptic ulcers and other gastrointestinal disorders including hyperacidit...