|Description||Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner.|
Benzcyclane, also called as Bencyclane or Benzcyclan, is a platelet aggregation inhibitor and used as a vasodilator effective.
SID 7969543 is a selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor (IC50 = 0.76, >33 and >33 μM at SF-1, RORα and VP16, respectively). It also inhibits S...
Astragaloside IV has cardiovascular protective effects. It can protect the vascular endothelial cells. Meanwhile, it also have antiinflammatory and anti-virus e...
Mastoparan, a tetradecapeptide which is a component of wasp venom, activates Gi and Go and has been shown to cause an increase in the production of Arachidonic ...
Gly-Phe-Arg, a superpotent synthetic tripeptide, mimics the mud-crab pumping pheromone.
IKarisoside A is a natural compound isolated from Epimedium koreanum, which has anti-inflammatory properties.
DPY-3050 is a useful intermediate for chemical synthesis of a number of biologically active drugs.
U-75875 is a protease inhibitor. It is also a peptidomimetic inhibitor and could inhibit HIV-1 gag-pol protein. It completely blocked HIV replication in human p...
Acetyl-Calpastatin (184-210) (human)
Acetyl-Calpastatin (184-210) (human) is a calpain I/II inhibitor and could increase secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitativ...
Mycophenolate mofetil hydrochloride
Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respect...
A derivative of psoralen, which intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks.
TMPA is an antagonist of nuclear receptor Nur77 (Kd = 1.45 ± 0.35 μM) and LKB1 interaction.
AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (...
Midodrine is an α1-receptor agonist and exerts its actions via activation of the alpha-adrenergic receptors of the arteriolar and venous vasculature.
Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide for control of postemergence annual grasses in crop fields.
CCMQ is an inhibitor of homoquinolinic acid binding to non-NMDA sensitive sites. It is combined with [3H]-homoquinolinic acid to characterize NR2B-containing NM...
EN460 is a small molecule inhibitor by EN460 binding to ERO1α to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme(IC50=1.9 uM) .
GnRH-I, a small 10 amino acid long peptide (decapeptide) from the hypothalamus, has previously been demonstrated and shown to be biologically active in the immu...
MZ 1, a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4), retains high affinity for BRD2, BRD3 and B...