|Description||Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner.|
LY 140091 is a bio-active chemical, but no detailed information has been published yet.
This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 an...
Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.
JNJ-39327041 is a bio-active chemical compound.
Tetrahydrouridine, a derivative of Uridine, is a potent and reversible competitive inhibitor of cytidine deaminase (CDD) (Ki values = 54 and 240 nM for human an...
Ancriviroc, an oximino-piperidino-piperidine-amide, is a CCR5 receptor antagonist.
STK321130 is potent FLT3 inhibitor with IC50 value of less than 1 μM.
Amrubicin is a novel anthracycline derivative for treatment of bladder carcinoma.
AMZ30, a PME-1 inhibitor, could inhibit PME-1 irreversiblely and be significant in the pharmacological study of determinating the demethylated PP2A function. IC...
Benzoylpaeoniflorin was found to be active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.
BPD-Ring B is a product from the synthesis of verteporfinin. It can be used for making porphyrin-related dye, nanoparticles, photosensitizers, and other photody...
Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central ...
TAK-603, a quinoline derivative, has been found to be an immunomodulator that was once studied in sorts of inflammatory diseases.
PLP(139-151), a synthetic myelin proteolipid protein (PLP) fragment, induces experimental autoimmune encephalomyelitis (EAE).
Tiamulin Fumarate is a derivative of Pleuromutilin, acts as an antibacterial.
O-Desmethyl Mebeverine Acid
O-Desmethyl Mebeverine Acid is a metabolite of Mebeverine, which is an antispasmodic.
Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various d...
Mitiglinide is a succinic acid derivative with hypoglycemic activity. It belongs to the meglitinide class of blood glucose-lowering drugs. It is a drug for the ...
KT 5823 is a cell-permeable, selective inhibitor of cGMP-dependent protein kinase (PKG) (Ki values are 0.23, 4 and > 10 μM for inhibition of PKG, PKC and PKA re...
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM).