I-BRD9 - CAS 1714146-59-4
Catalog number:
1714146-59-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H22F3N3O3S2
Molecular Weight:
497.55
COA:
Inquire
Targets:
BET Bromodomain
Description:
I-BRD9, as a selective cell active chemical probe for BRD9 (pIC50 = 7.3), it exhibits 200-fold selectivity for bromodomain containing protein 9 over the highly homologous BRD7 bromodomain, >70-fold selectivity for BRD9 over a panel of 34 other bromodomain
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Appearance:
Solid powder
Synonyms:
N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide I-BRD9 N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamide G
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in 1eq. HCl
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -75℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
683.9±65.0 °C | Condition: Press: 760 Torr
Density:
1.50±0.1 g/cm3
InChIKey:
WRUWGLUCNBMGPS-UHFFFAOYSA-N
InChI:
1S/C22H22F3N3O3S2/c1-2-28-12-17(13-4-3-5-14(10-13)22(23,24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30,31)9-7-15/h3-5,10-12,15H,2,6-9H2,1H3,(H2,26,27)
Canonical SMILES:
CCN1C=C(C2=C(C1=O)C=C(S2)C(=NC3CCS(=O)(=O)CC3)N)C4=CC(=CC=C4)C(F)(F)F
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