|Description||Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.|
Tiotropium Bromide, an azoniatricyclo derivative, is a mAChR antagonist that could be used as bronchodilation agent and smooth muscle relaxant.
Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic.
Vinconate, a vinca alkaloid derivative, can stimulate the muscariic acetylcholine receptor. Vinconate prevents ischemic neuronal damage by direct action on the ...
Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms.
Nuvenzepine, a new pirenzepine-analog, is an mAChR antagonist, administered intraduodenally, displayed a long-lasting and dose-dependent inhibition of neostigmi...
PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM).
VU 0357017 hydrochloride
The hydrochloride salt form of VU0357017 which is a selective M1 agonists and has been found to be probably effective in the treatment of hippocampal-dependent ...
Anisodamine is a alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine by binding in brain membrane preparations.
BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration o...
mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.
Xanomeline is a Muscarinic M1 and M4 receptor agonist under the development of Eli Lilly, though it is also known to act as a M5 receptor antagonist. Xanomeline...
Methscopolamine is a muscarinic acetylcholine receptor blocker.
Camylofine dihydrochloride is an antimuscarinic used as a smooth muscle relaxant.
Tiotropium Bromide hydrate
Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a mus...
Pirmenol, also known as CI-845, a new antiarrhythmic drug, inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. However, pirm...
M3 receptor antagonist 1
An antagonist of muscarinic M3-receptor
Trospium chloride is a competitive muscarinic cholinergic receptor antagonist.
Atropine sulfate salt monohydrate
Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...