Hydroxyzine dihydrochloride - CAS 2192-20-3
Catalog number: 2192-20-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H27ClN2O2.2HCl
Molecular Weight:
447.83
COA:
Inquire
Targets:
Histamine Receptor
Description:
Hydroxyzine (sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
Hydroxyzine dihydrochloride, Hydroxyzine hydrochloride, Vistaril, Atarax
MSDS:
Inquire
1.Efficacy of the Sequential Administration of Melatonin, Hydroxyzine, and Chloral Hydrate for Recording Sleep EEGs in Children.
Dirani M1, Nasreddine W1, Melhem J1, Arabi M2, Beydoun A3. Clin EEG Neurosci. 2016 Jan 10. pii: 1550059415621830. [Epub ahead of print]
Sedation of children for electroencephalography (EEG) recordings is often required. Chloral hydrate (CH) requires medical clearance and continuous monitoring. To try to reduce personnel and time resources associated with CH administration, a new sedation policy was formulated. This study included all children who underwent an EEG during a consecutive 3-month period following the implementation of the new sedation policy, which consists of the sequential administration of melatonin, hydroxyzine (if needed), and CH (if needed). The comparator group included all children with a recorded EEG during a consecutive 3-month period when the sedation policy consisted of the sole administration of CH. A total of 803 children with a mean age of 7.9 years (SD = 5.1, range = 0.5-17.7 years) were included. Sleep EEG recordings were obtained in 364 of 385 children (94.6%) using the old sedation policy and in 409 of 418 children (97.9%) using the new one.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Histamine Receptor Products


CAS 73903-17-0 JNJ-10191584

JNJ-10191584
(CAS: 73903-17-0)

JNJ-10191584 is a selective histamine H4 receptor antagonist. It inhibits mast cell in vitro with IC50 value of 138nM. JNJ-10191584 has antiinflammatory and ana...

CAS 720690-73-3 GSK 189254A

GSK 189254A
(CAS: 720690-73-3)

GSK-189,254 is a H3 histamine receptor inverse agonist. It has subnanomolar affinity for the H3 receptor with Ki of 0.2nM. It possesses stimulant and nootropic ...

CAS 13461-01-3 aceprometazine

aceprometazine
(CAS: 13461-01-3)

Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders su...

CAS 190786-44-8 Bepotastine Besilate

Bepotastine Besilate
(CAS: 190786-44-8)

Bepotastine stimulates P-gp-mediated ATP hydrolysis with Km, Vmax, and Vmax/Km values of 1.25 mM, 108 nmol/min/mg protein, and 0.087 mL/min/mg protein, respecti...

ABT-239
(CAS: 460746-46-7)

ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophr...

CAS 59-33-6 Pyrilamine maleate salt

Pyrilamine maleate salt
(CAS: 59-33-6)

Pyrilamine maleate salt is a first generation antihistamine and binds with high affinity to G(q/11) protein. It is commonly utilized as a radioligand binding as...

CAS 184025-19-2 Ciproxifan maleate

Ciproxifan maleate
(CAS: 184025-19-2)

Ciproxifan maleate, also called as FUB-359 maleate, is a highly potent and strongly selective histamine H3 inverse agonist/antagonist (IC50 = 9.2 nM) which disp...

CAS 562-10-7 Doxylamine Succinate

Doxylamine Succinate
(CAS: 562-10-7)

Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.

CAS 5053-06-5 Fenspiride

Fenspiride
(CAS: 5053-06-5)

Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...

CAS 5638-76-6 Betahistine

Betahistine
(CAS: 5638-76-6)

Betahistine is a H1 receptor agonist, which serves as a vasodilator. It is used in Meniere disease and in vascular headaches but may exacerbate bronchial asthma...

CAS 202189-78-4 Bilastine

Bilastine
(CAS: 202189-78-4)

Bilastine is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

CAS 7456-24-8 Fonazine

Fonazine
(CAS: 7456-24-8)

Dimetotiazine is a histamine H1 receptor antagonist. It is a phenothiazine drug used for the treatment of migraine.

CAS 113-69-9 Benzquinamide Hydrochloride

Benzquinamide Hydrochloride
(CAS: 113-69-9)

Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...

Mizolastine dihydrochloride
(CAS: 1056596-82-7)

The dihydrochloride salt form of Mizolastine which is effective in the treatment of seasonal allergic rhinitis, perennial allergic rhinitis and other allergy sy...

CAS 3964-81-6 Azatadine

Azatadine
(CAS: 3964-81-6)

Azatadine is a new antihistamine acts as histamine for histamine H1- receptor inhibitor ( IC50 = 6.5 nM and 10 nM, respectively).

CAS 132-21-8 dexbrompheniramine

dexbrompheniramine
(CAS: 132-21-8)

Dexbrompheniramine is an histamine H1-receptor antagonist used for the treatment of allergic conditions including hay fever or urticaria. It is the pharmacologi...

CAS 1104-22-9 Meclizine 2HCl

Meclizine 2HCl
(CAS: 1104-22-9)

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation...

CAS 100643-71-8 Desloratadine

Desloratadine
(CAS: 100643-71-8)

Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.

GSK-239512
(CAS: 720691-69-0)

GSK-239512 is a histamine H3 receptor antagonist. In Jun 2015, Phase-II for Schizophrenia in USA was discontinued. Phase II clinical trilas for the treatment of...

CAS 34580-13-7 Ketotifen

Ketotifen
(CAS: 34580-13-7)

Ketotifen is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators, used as self-medication for the temporary relief of ...

Chemical Structure

CAS 2192-20-3 Hydroxyzine dihydrochloride

Quick Inquiry

Verification code

Featured Items