HX-603 - CAS 259228-72-3
Catalog number: 259228-72-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31H34N2O2
Molecular Weight:
466.625
COA:
Inquire
Targets:
RAR/RXR
Description:
HX-603 is a RXR agonist.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Appearance:
White to Off-White Solid
Synonyms:
4-(7,7,10,10-tetramethyl-5-propyl-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid; HX-603; HX 603; HX603
MSDS:
Inquire
Boiling Point:
483.2±40.0 ℃ at 760 mmHg
Density:
1.2±0.1 g/cm3
InChIKey:
QGNIEQLYJAHKHG-UHFFFAOYSA-N
InChI:
1S/C31H34N2O2/c1-6-17-33-26-10-8-7-9-25(26)32-28(20-11-13-21(14-12-20)29(34)35)22-18-23-24(19-27(22)33)31(4,5)16-15-30(23,2)3/h7-14,18-19H,6,15-17H2,1-5H3,(H,34,35)
Canonical SMILES:
CCCN1C2=CC=CC=C2N=C(C3=CC4=C(C=C31)C(CCC4(C)C)(C)C)C5=CC=C(C=C5)C(=O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related RAR/RXR Products


CAS 859498-05-8 AGN 205728

AGN 205728
(CAS: 859498-05-8)

AGN 205728 is a potent and selective RARγ antagonist and has no inhibiton on RARα and RARβ.

CAS 911110-93-5 Adapalene sodium salt

Adapalene sodium salt
(CAS: 911110-93-5)

Adapalene sodium salt, a synthetic retinoid, is a Retinoic acid receptor agonist (RAR). It is a third-generation topical retinoid primarily used in the treatmen...

CAS 107430-66-0 CD1530

CD1530
(CAS: 107430-66-0)

CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It ...

CAS 106685-40-9 Adapalene

Adapalene
(CAS: 106685-40-9)

Adapalene is more active than indomethacin, betamethasone valerate, tretinoin, isotretinoin or etretinate in inhibiting lipoxygease activity, but it has little ...

AGN 195183
(CAS: 367273-07-2)

RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and pr...

CAS 65646-68-6 Fenretinide

Fenretinide
(CAS: 65646-68-6)

Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenreti...

CAS 71441-28-6 TTNPB

TTNPB
(CAS: 71441-28-6)

TTNPB potently and selectively activates retinoic acid receptors (EC50s = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively). And it does not act on reti...

CAS 102121-60-8 AM580

AM580
(CAS: 102121-60-8)

AM580 is a stable retinobenzoic derivative originally synthesized as a RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively).

CAS 55079-83-9 Acitretin

Acitretin
(CAS: 55079-83-9)

Acitretin is a second generation retinoid used for psoriasis.

CAS 94497-51-5 Tamibarotene

Tamibarotene
(CAS: 94497-51-5)

Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation and apoptosis of HL-60 cells in vitro. It exhibits antiproliferative effe...

LY 2955303 hydrochloride

LY 2955303 hydrochloride is a potent and selective retinoic acid receptor gamma (RARγ) antagonist (Ki values >1700 nM, >2980 nM, and 1.1 nM for RARα, RARβ, and ...

CAS 262433-54-5 BMS 270394

BMS 270394
(CAS: 262433-54-5)

BMS 270394 is a nuclear retinoic acid receptor (RAR-γ) agonist.

CAS 229961-45-9 AGN 194310

AGN 194310
(CAS: 229961-45-9)

A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs = 2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to...

NRX-204647
(CAS: 1351452-80-6)

NRX-204647 is a Retinoic acid receptor gamma-selective inverse agonist.

CAS 153559-49-0 Bexarotene

Bexarotene
(CAS: 153559-49-0)

Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.

UAB30
(CAS: 205252-59-1)

UAB30 is a low-toxicity retinoid X receptor-selective agonist selective for the binding and activation of RXR’s over RAR' s. UAB30 is highly effective in the pr...

CAS 410528-02-8 Palovarotene

Palovarotene
(CAS: 410528-02-8)

Palovarotene is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. In small animal studies, palovarotene was claimed to rev...

HX-603
(CAS: 259228-72-3)

HX-603 is a RXR agonist.

LY2955303
(CAS: 1433497-19-8)

LY2955303 is a selective Retinoic acid receptor gamma (RAR-γ) antagonist with Ki of 1.09 nM; (RAR-α Ki > 1700 nM; RAR-β Ki > 2980 nM). LY2955303 showed good pha...

CAS 118292-40-3 Tazarotene

Tazarotene
(CAS: 118292-40-3)

Tazarotene could propel either early or late portions of the period leading to differentiation and G0 arrest and is interchangeable with an RARalpha-selective l...

Quick Inquiry

Verification code

Featured Items