A dual COX-1/COX-2 inhibitor
This active molecular is selective mPGES-1 (microsomal prostaglandin E synthase-1 inhibitor. mPGES-1 is an enzyme induced during the inflammatory response and i...
PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) (IC50= 0.28 μM) and also an inhibitor of 5-lipoxygenase (IC50= 1.05 μM).
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain ...
SAR191801 is a hPGDS inhibitor and the IC50 value of which is 12 nM that was determined through fluorescence polarization.
Mesalamine is an anti-inflammatory compound.
Pranoprofen (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM.
Zomepirac sodium salt is a prostaglandin synthetase inhibitor, was indicated for the management of mild to severe pain.