Homo sildenafil - CAS 642928-07-2
Catalog number: 642928-07-2
Molecular Formula:
C23H32N6O4S
Molecular Weight:
488.61
COA:
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Description:
Homosildenafil, also known as methyl-sildenafil, is a synthetic drug which acts as a phosphodiesterase inhibitor. It is an analog of sildenafil and vardenafil.
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Purity:
> 95%
Appearance:
White to Light Beige Solid
Synonyms:
5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;
MSDS:
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Quantity:
Milligrams-Grams
Melting Point:
>190ºC
1.[Strategies of sperm collection from men with temporary penile erectile dysfunction on the day of oocyte retrieval and the outcomes of IVF-ET].
Xu HY, Deng K, Luo QB, Zhang X, Li X, Zhang CJ. Zhonghua Nan Ke Xue. 2015 Dec;21(12):1093-7.
OBJECTIVE: To search for the optimal strategies for sperm collection from the patient with temporary penile erectile dysfunction (ED) on the day of oocyte pick-up ( OPU) in in vitro fertilization embryo transfer (IVF-ET).
2.[Rapid screening and confirmation of illegally added anti- impotence preparations in health care products by high performance liquid chromatography-high resolution mass spectrometry].
Hu T, Qu X, Kang M, Song Q, Yang L, Zhao Y, Zhang D. Se Pu. 2015 Aug;33(8):897-901.
A method was established for rapid screening and quantifying 11 illegally added anti-impotence preparations (yohimbine, acetildenafil, nor-acetildenafil, homosildenafil, hydroxy-homosildenafil, sildenafil, vardenafil, thioaildenafil, tadalafil, pseudovardenafil, dapoxetine) in health care products by high performance liquid chromatography-high resolution mass spectrometry. The samples were extracted with methanol and analyzed by positive mode in the MS detection. The results showed that the limits of detection were 25.0 ng/mLexcept for nor-acetildenafil (5.0 ng/mL), the linear ranges were 5.0-200.0 ng/mL except for nor-acetildenafil (25.0-500.0 ng/mL) with the correlation coefficients not less than 0.999 0. The recoveries were in the range of 82.0%-105.9% with the relative standard deviations of 4.7%-16.5%. This method is accurate, simple and rapid, and can be used in rapid screening and quantitative analysis of the 11 illegally added anti-impotence in health care products.
3.Sildenafil Treatment of Infants With Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.
Backes CH1, Reagan PB2, Smith CV3, Jadcherla SR4, Slaughter JL5. Hosp Pediatr. 2016 Jan;6(1):27-33. doi: 10.1542/hpeds.2015-0076. Epub 2015 Jan 1.
OBJECTIVE: This study had 2 goals: (1) to identify clinical and demographic characteristics associated with sildenafil exposure for infants with bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH); and (2) to characterize hospital-specific treatment frequency, age at first administration, and length of sildenafil treatment.
4.You're the Flight Surgeon: erectile dysfunction.
Puchta P. Aerosp Med Hum Perform. 2016 Feb;87(2):152-5. doi: 10.3357/AMHP.4419.2016.
Puchta P. You're the flight surgeon: erectile dysfunction. Aerosp Med Hum Perform. 2016; 87(2):152-155.
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CAS 642928-07-2 Homo sildenafil

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