Homatropine Methylbromide - CAS 80-49-9
Catalog number: 80-49-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C17H24BrNO3
Molecular Weight:
370.28
COA:
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Targets:
mAChR (WKY-E)
Description:
Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
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Purity:
>98%
MSDS:
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1.Myomatous hepatic angiomyolipoma: imaging findings in 14 cases with radiological-pathological correlation and review of the literature.
Zhu Z1, Yang L, Zhao XM, Luo DQ, Zhang HT, Zhou CW. Br J Radiol. 2014 Jun;87(1038):20130712. doi: 10.1259/bjr.20130712. Epub 2014 Mar 27.
OBJECTIVE: To display and analyse the imaging features of myomatous hepatic angiomyolipomas (MHAMLs).
2.Preparation of a β-Cyclodextrin-Based Open-Tubular Capillary Electrochromatography Column and Application for Enantioseparations of Ten Basic Drugs.
Fang L1, Yu J1, Jiang Z1, Guo X1. PLoS One. 2016 Jan 15;11(1):e0146292. doi: 10.1371/journal.pone.0146292. eCollection 2016.
An open-tubular capillary electrochromatography column was prepared by chemically immobilized β-cyclodextrin modified gold nanoparticles onto new surface with the prederivatization of (3-mercaptopropyl)-trimethoxysilane. The synthesized nanoparticles and the prepared column were characterized by transmission electron microscopy, scanning electron microscopy, infrared spectroscopy and ultraviolet visible spectroscopy. When the column was employed as the chiral stationary phase, no enantioselectivity was observed for ten model basic drugs. So β-cyclodextrin was added to the background electrolyte as chiral additive to expect a possible synergistic effect occurring and resulting in a better separation. Fortunately, significant improvement in enantioselectivity was obtained for ten pairs of drug enantiomers. Then, the effects of β-cyclodextrin concentration and background electrolyte pH on the chiral separation were investigated. With the developed separation mode, all the enantiomers (except for venlafaxine) were baseline separated in resolutions of 4.
3.Is surgery necessary for patients with hepatic angiomyolipoma? Retrospective analysis from eight Chinese cases.
Yang L1, Xu Z, Dong R, Fan J, Du Y, Zhang Y, Wang X, Cheng X, Guo J. J Gastroenterol Hepatol. 2013 Oct;28(10):1648-53. doi: 10.1111/jgh.12289.
BACKGROUND AND AIM: Hepatic angiomyolipoma (AML) is a rare, hepatic mesenchymal neoplasm. Its preoperative diagnosis is very difficult, and the treatment is still controversial. The aim is to summarize experience in diagnosis and management of hepatic AML from a cancer center.
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CAS 80-49-9 Homatropine Methylbromide

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