|Description||HLM 006474 acts as an E2F transcription factor inhibitor, preventing DNA binding activity. This results in the induction of apoptosis in breast cancer cells.|
|Synonyms||HLM 006474; HLM-006474|
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).
Clofazimine stimulates oxygen consumption and superoxide generation by neutrophils, Clofazimine also causes phospholipase A2 activation in neutrophils, resultin...
Epimedin B, a flavonoids natural product extracted from Herbal Epimedium, has been studied to have potential antiosteoporotic effect.
ML281, a quinoxalin derivative, has been found to be a STK33 inhibitor and could have probable effect against KRAS-dependent cancers. IC50: 14 nM.
Microorganisms commonly accumulate at interfaces as part of biofilms held together by a matrix of hydrated extracellular polymeric substances. cis-2-Decenoic ac...
Cholesterol is the principal sterol of all higher animals required to build and maintain membranes.
3PO, as a small molecule competitive inhibitor of HIF-1-induced PFKFB3 it has the potential to suppress tumor glucose metabolism and growth of non-small cell lu...
SPDB, a pyridyldithioyl compound, has been found to link to DM4 conjugates and probably influence the releasement of cytotoxic metabolitesin.
DL-Glutamine is an unnatural amino acid and could be used for general biochemical research and drug synthesis.
EAD-1, a chloroquinoline derivative, has been found to be an autophagy inhibitor that exhibit antiproliferative effct in lung and pancreatic cancer cells so tha...
The hydrochloride salt form of Oxyphencyclimine which could influence the peripheral parasympathetic system and increase the stomach secretions.
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respec...
SID 3712249 is an biogenesis of microRNA-544 (miR-544) inhibitor caused apoptosis in triple negative breast cancer cells.
Methasulfocarb is a fungicide compound.
Herzuma is a biosimilar of trastuzumab approved by EU for the treatment of patients with early breast cancer, metastatic breast cancer or metastatic gastric can...
Melinamide, also known as AC-223 or Artes, an amide derivative of an unsaturated long-chain fatty acid, is a new hypocholesterolaemic drug, caused a substantial...
Lificiguat, also known as YC-1, is a inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). YC-1 is widely used as a potent inhibitor of HIF-1alpha both in ...
CP-67015 has inhibitory effect on topoisomerase function. It is a direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.
Benzyl benzoate, extracted from Cinnamomum zeylanicum leaves and stem bark, could be used as a pediculicide.