|Description||HLM 006474 acts as an E2F transcription factor inhibitor, preventing DNA binding activity. This results in the induction of apoptosis in breast cancer cells.|
|Synonyms||HLM 006474; HLM-006474|
YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).YK-4-279 eliminates cyclin D levels by blocking the interaction of EWS-FLI1 with RHA ...
The D-Tartrate salt form of Isofagomine, an imino pyranose compound, has been found to be a glucosylceramidase stimulant and could exhibit activity in Gaucher's...
D-Luciferin sodium salt
Sodium salt form of D-Luciferin, derived from the luciferase gene of photinus pyralis, is commonly used as a reporter gene for studying transcriptional regulati...
3PO, as a small molecule competitive inhibitor of HIF-1-induced PFKFB3 it has the potential to suppress tumor glucose metabolism and growth of non-small cell lu...
HJC0197 is a erythromycin propionate-N-acetylcysteinate inhibitor (EPAC). IC50 value is 5.9 µM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange a...
Gastrin-Releasing Peptide, human
Gastrin-Releasing Peptide, human (GRP), one of the bombesin-like peptide family, is an agonist for the gastrin-releasing peptide receptor (GRPR) and it plays on...
Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.
CVT10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50 value of 29nM, thereby inhibiting dopamine synthesis. It ...
SSM 3 trifluoroacetate
SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM) which blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro...
LP-935509 is a brain penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50 value 3.3 nM and 14 nM and 320 nM for the closely related BIKE and...
GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to a...
Isoastragaloside II is an astragaloside, which is isolated from the hairy root culture of Astragalus membranaceus.
2-Hydroxybenzyl alcohol could be extracted from salix bark. And this is the reason for 2-Hydroxybenzyl alcohol being named "Salicyl alcohol". It is an precursor...
Pep 2-8 is a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor.
A synthetic leptin peptide fragment
Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents, which is used for the ...
SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent...
AM-206 is a bio-active chemical but no detailed data has been published yet.
FMRF is a peptide consisting of 4 amino acid residues.
CGS 35066 is a potent endothelin-converting enzyme (ECE) inhibitor with > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 = 22 and 2300 nM, respecti...