HJC0197 - CAS 1383539-73-8
Catalog number:
1383539-73-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H21N3OS
Molecular Weight:
339.45
COA:
Inquire
Targets:
Others
Description:
HJC0197 is a erythromycin propionate-N-acetylcysteinate inhibitor (EPAC). IC50 value is 5.9 µM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange activity at 25 µM, but it has no effect on cAMP-induced type I and II PKA activity at this concentration . HJC0197 can be used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion.
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Purity:
98%
Appearance:
A crystalline solid
Synonyms:
4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
study the role of Epac signaling
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
QLLWRTHDHRGHQZ-UHFFFAOYSA-N
InChI:
1S/C19H21N3OS/c1-12-7-8-13(2)15(9-12)11-24-19-21-17(14-5-3-4-6-14)16(10-20)18(23)22-19/h7-9,14H,3-6,11H2,1-2H3,(H,21,22,23)
Canonical SMILES:
CC(C=CC(C)=C1)=C1CSC(NC(C2CCCC2)=C3C#N)=NC3=O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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