|Description||HJC0197 is a erythromycin propionate-N-acetylcysteinate inhibitor (EPAC). IC50 value is 5.9 µM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange activity at 25 µM, but it has no effect on cAMP-induced type I and II PKA activity at this concentration . HJC0197 can be used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion.|
|Appearance||A crystalline solid|
|Solubility||Soluble in DMSO|
|Application||study the role of Epac signaling|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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