HI TOPK 032 - CAS 487020-03-1
Catalog number: 487020-03-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H11N5OS
Molecular Weight:
369.4
COA:
Inquire
Targets:
Others
Description:
HI TOPK 032 is a novel TOPK inhibitor as a T-LAK-cell-originated protein kinase (TOPK) inhibitor, blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 µM and providing complete inhibition at 5 µM.
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Purity:
≥98%
Appearance:
Red solid
Synonyms:
N-(12-Cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A novel TOPK inhibitor
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
BCSBXWKRZUPFHW-UHFFFAOYSA-N
InChI:
1S/C20H11N5OS/c21-11-13-16-10-12(22-20(26)17-6-3-9-27-17)7-8-25(16)19-18(13)23-14-4-1-2-5-15(14)24-19/h1-10H,(H,22,26)
Canonical SMILES:
O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2
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