|Description||HI TOPK 032 is a novel TOPK inhibitor as a T-LAK-cell-originated protein kinase (TOPK) inhibitor, blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 µM and providing complete inhibition at 5 µM.|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||A novel TOPK inhibitor|
|Quality Standard||Enterprise Standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.|
Atomoxetine is a norepinephrine reuptake inhibitor approved for the treatment of attention deficit hyperactivity disorder (ADHD).
Flurofamide is a bacterial urease inhibitor used for the treatment of gastritis and irregular urease activity in the urinary tract.
K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, w...
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory ac...
15(R)-17-phenyl trinor Prostaglandin F2α
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 ...
Mechlorethamine is the prototype of alkylating agents, it works by binding to DNA, crosslinking two strands and preventing cell duplication.
GSK-1071306 is one of the metabolites of pazopanib which is a inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity as a approve...
NDT 9513727 is a C5a receptor (C5aR) antagonist with IC50 value of 11.6 nM. NDT 9513727 can inhibit C5a-induced neutropenia in gerbil and cynomolgus macaque. In...
Famprofazone, known to metabolize to Methamphetamine and Amphetamine, is a non-steroidal anti-inflammatory agent (NSAID).
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.
Fatostatin A hydrobromide
Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic (ob/ob) mice, and inhibits pr...
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
Benzyl alcohol, an aromatic alcohol compound, could be found in many sorts of essential oils with the FEMA number: 2137.
Pinoresinol Diglucoside, one of the major lignans with various pharmacological activities, is a sugar lignan which inhibits α-glucosidase in vitro.
DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 subst...
MK 0434 is a Cholestenone 5-alpha reductase inhibitor originated by Merck & Co and it is associated with a significant reduction in dihydrotestosterone. No deve...
Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specif...
XCT 0315908, a RXR agonist, showed selectivity for RXR−Nurr1 over a broad range of other RXR dimerization partners but with rather low potency.
Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Isoxazole 9 (ISX-9)
Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs).