HG6-64-1 - CAS 1315329-43-1
Catalog number: 1315329-43-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C32H34F3N5O2
Molecular Weight:
577.64
COA:
Inquire
Targets:
Raf
Description:
HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
HG-6-64-1; HG 6-64-1
MSDS:
Inquire
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Raf Products


ARQ 736 disodium salt
(CAS: 1228237-57-7)

This active molecular is a Proto oncogene protein b raf and Vascular endothelial growth factor A inhibitor originated by ArQule. ARQ 736 is effective in killing...

CAS 90719-30-5 Locostatin

Locostatin
(CAS: 90719-30-5)

Locostatin is a Raf kinase inhibitory protein (RKIP) inhibitor that disrupts the interaction of RKIP with Raf-1 kinase and GRK2. Locostatin is also an inhibitor...

CAS 918505-84-7 PLX4720

PLX4720
(CAS: 918505-84-7)

PLX4720 is a 7-azaindole derivative that inhibits B-Raf(V600E) with an IC(50) of 13 nM, defines a class of kinase inhibitor with marked selectivity in both bioc...

BGB-283
(CAS: 1446090-77-2)

BGB-283 is a selective Epidermal growth factor receptor and Proto oncogene protein b raf inhibitor under the development of BeiGene. BGB-283 shows antitumor act...

CAS 1188910-76-0 CEP-32496

CEP-32496
(CAS: 1188910-76-0)

CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respec...

AMG-628
(CAS: 862269-73-6)

AMG-628 is a highly selective, ATP-competitive inhibitor of Raf kinases. It can inhibit activation of tyrosine protein kinases. AMG-628 can also inhibit growth,...

Encorafenib
(CAS: 1269440-29-0)

Encorafenib is a Proto oncogene protein b raf inhibitor with potential antineoplastic activity. By inhibiting the activation of the RAF/MEK/ERK signaling pathwa...

CAS 1237536-18-3 ML 786 dihydrochloride

ML 786 dihydrochloride
(CAS: 1237536-18-3)

ML786 dihydrochloride is a Raf kinase inhibitor with IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively. It may be used ...

CAS 220904-83-6 GW5074

GW5074
(CAS: 220904-83-6)

GW5074 is a c-Raf inhibitor. GW5074 has no direct effect on the activities of several apoptosis-associated kinases when assayed in vitro. In contrast to its eff...

CAS 1191385-19-9 B-Raf inhibitor 1 dihydrochloride

B-Raf inhibitor 1 dihydrochloride
(CAS: 1191385-19-9)

B-Raf inhibitor 1 is an inhibitor of B-Raf kinase with IC50 values of 0.31μM and 0.72μM for cell proliferation, respectively in A375 and HCT116. B-Raf is import...

PLX8394
(CAS: 1393466-87-9)

PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf (BRAF) protein with potential antineoplastic activity. PLX8394 appears to s...

CAS 918504-65-1 Vemurafenib

Vemurafenib
(CAS: 918504-65-1)

Vemurafenib is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity than...

CAS 284461-73-0 Sorafenib

Sorafenib
(CAS: 284461-73-0)

Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

CAS 905281-76-7 GDC-0879

GDC-0879
(CAS: 905281-76-7)

GDC-0879, a highly selective, potent, and orally bioavailable RAF small-molecule inhibitor. In GDC-0879-treated mice, both cell line- and patient-derived BRAF(...

CAS 1315329-43-1 HG6-64-1

HG6-64-1
(CAS: 1315329-43-1)

HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.

CAS 1195765-45-7 Dabrafenib (GSK2118436)

Dabrafenib (GSK2118436)
(CAS: 1195765-45-7)

Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.

CAS 927880-90-8 RAF265

RAF265
(CAS: 927880-90-8)

RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30...

CAS 918505-61-0 BRAF inhibitor

BRAF inhibitor
(CAS: 918505-61-0)

BRAF inhibitor is a potent BRAF inhibitor.

MCP110
(CAS: 521310-51-0)

MCP110 is an Ras/Raf-1 interaction inhibitor. The Ras signaling pathway is activated either by direct mutation of Ras or its effector B-Raf. MCP110 was shown to...

CCT241161
(CAS: 1163719-91-2)

This active molecular is a novel , paradox-breaking pan-RAF inhibitor with anti-SRC activity and it blocked growth of BRAF-mutant and NRAS-mutant melanoma cells...

Chemical Structure

CAS 1315329-43-1 HG6-64-1

Quick Inquiry

Verification code

Featured Items