Heptaminol Hydrochloride - CAS 543-15-7
Catalog number: 543-15-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C8H19NO
Molecular Weight:
181.7
COA:
Inquire
Targets:
Others
Description:
Heptaminol Hydrochloride is an amino alcohol which is classified as a vasoconstrictor used in the treatment of low blood pressure, particularly orthostatic hypotension.
Purity:
≥95%
Appearance:
White solid
Synonyms:
6-Amino-2-methyl-2-heptanol hydrochloride; Cardiosintol;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A vasoconstrictor
Quality Standard:
Enterprise Standard/EP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
JZNBMCOSOXIZJB-UHFFFAOYSA-N
InChI:
1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H
Canonical SMILES:
CC(CCCC(C)(C)O)N.Cl
1.Absorption, distribution, elimination and metabolism of 14C-heptaminol hydrochloride in rat.
Chanoine F, Benedetti MS, Ancher JF, Dostert P. Arzneimittelforschung. 1981;31(9):1430-5.
Absorption, distribution, excretion and metabolism studies with 14C-labelled 6-amino-2-methyl-2-heptanol hydrochloride (14C-heptaminol hydrochloride, Hept-amyl) were carried out in rat. After a 10 mg/kg p.o. dose heptaminol was rapidly and entirely absorbed. Following the administration of 8 mg/kg i.v. or 12 mg/kg p.o., all tissues studied, except brain, contained higher levels of radioactivity than did plasma. No evidence of accumulation of the drug was seen in any tissue. Whole-body autoradiography revealed a preferential localisation in salivary glands, hypophysis and adrenal medulla 1 h after a 10 mg/kg i.v. or p.o. dose. Brain autoradiography showed radioactivity localised only in highly vascularised areas (choroid plexus and pia mater). Excretion occurred mainly by kidney, 68% of the radioactivity being excreted in urine 4 h after a dose of 10 mg/kg i.v. Biliary and faecal elimination accounted for less than 1% of the radioactivity administered.
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CAS 543-15-7 Heptaminol Hydrochloride

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