HCV371 - CAS 675184-27-7
Catalog number: 675184-27-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C18H20N2O3
Molecular Weight:
312.37
COA:
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Targets:
NS5B polymerase
Description:
HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases.
Purity:
98%
Appearance:
Solid powder
Synonyms:
HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
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Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Boiling Point:
575.2±45.0 °C | Condition: Press: 760 Torr
Density:
1.29±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Canonical SMILES:
N#CC1=CC=C(C(N2)=C1C3=C2[C@](CCC)(OCC3)CC(O)=O)C
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