Harpagoside - CAS 19210-12-9
Catalog number: 19210-12-9
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H30O11
Molecular Weight:
494.49
COA:
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Description:
Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRNA levels. Harpagoside also inhibited protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells, which involves suppression of NF-kappaB activation, thereby inhibiting downstream inflammation and subsequent pain events
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Purity:
>98%
Appearance:
White Solid
Synonyms:
HARPAGOSIDE;8-O-E CINNAMOYL HARPAGIDE;8'-CINNAMOYLHARPAGIDE;Harpagosid;[1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside;Harpogoside;HARPAGOSIDE hplc;[(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate
MSDS:
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Application:
Anti-inflammatory
Quality Standard:
CP2010
Quantity:
Milligrams-Grams
Melting Point:
218-220℃
InChIKey:
KVRQGMOSZKPBNS-FMHLWDFHSA-N
InChI:
1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1
Canonical SMILES:
CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)OC(=O)C=CC4=CC=CC=C4
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CAS 19210-12-9 Harpagoside

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