H3B-6527 - CAS 1702259-66-2
Catalog number:
1702259-66-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C29H34Cl2N8O4
Molecular Weight:
629.543
COA:
Inquire
Targets:
FGFR
Description:
H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity.
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Brife Description:
An orally active FGFR4 inhibitor
Appearance:
Solid powder
Synonyms:
N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527
Solubility:
Soluble to ≥ 6.3 mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Boiling Point:
832.1±65.0 °C | Condition: Press: 760 Torr
Density:
1.373±0.06 g/cm3
InChIKey:
MBWRLLRCTIYXDW-UHFFFAOYSA-N
InChI:
1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)
Canonical SMILES:
C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
Current Developer:
H3 Biomedicine
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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