GYY-4137 Morpholine salt - CAS 106740-09-4
Catalog number:
106740-09-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H25N2O3PS2
Molecular Weight:
376.47
COA:
Inquire
Targets:
Others
Description:
GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation.
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥95%
Appearance:
White solid
Synonyms:
GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt
Solubility:
Soluble to 100 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
GYY-4137 Morpholine salt inhibits the inflammatory response. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Melting Point:
164-166 °C
InChIKey:
YZMHNNLDUWRZFW-UHFFFAOYSA-N
InChI:
InChI=1S/C11H16NO2PS2.C4H9NO/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2
Canonical SMILES:
COC1=CC=C(C=C1)P(=S)(N2CCOCC2)[S-].C1COCC[NH2+]1
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


PrP 106-126

PrP (106-126), a peptide corresponding to the prion protein (PrP) amyloidogenic region, interacted selectively with PBEC via their luminal side, and caused cumu...

CAS 1146963-51-0 J 147

J 147
(CAS: 1146963-51-0)

J 147, under the IUPAC name N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide, a phenyl hydrazide compound that has been...

BMS-214662 mesylate
(CAS: 474010-58-7)

BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor ...

CAS 541-15-1 L-carnitine

L-carnitine
(CAS: 541-15-1)

L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyper...

CAS 107668-79-1 Bulleyaconitine A

Bulleyaconitine A
(CAS: 107668-79-1)

Bulleyaconitine A, an active indegrent from aconitum bulleyanum Diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis.

CAS 1384071-99-1 AD80

AD80
(CAS: 1384071-99-1)

AD80, also called as A-196, is a multikinase inhibitor that inhibits against human BRAF, S6K, and SRC and shows strong activity against RET inhibitor.

CAS 30652-11-0 Deferiprone

Deferiprone
(CAS: 30652-11-0)

A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transf...

CAS 34367-04-9 Ginsenoside Ro

Ginsenoside Ro
(CAS: 34367-04-9)

Ginsenoside Ro, the predominant ginsenoside in the rhizome, shows no hemolytic nor cytotoxic activities.

APCP-363
(CAS: 340023-40-7)

APCP-363 a bio-active chemical.

CAS 34097-16-0 Clocortolone Pivalate

Clocortolone Pivalate
(CAS: 34097-16-0)

Clocortolone Pivalate is a Corticosteroid Hormone Receptor Agonist. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroi...

CAS 7770-78-7 Arctigenin

Arctigenin
(CAS: 7770-78-7)

Arctigenin is the aglycone of arctiin and is a lignan found in certain plants of the Asteraceae. It has shown antiviral and anticancer effects in glass. It show...

CAS 4618-18-2 Lactulose

Lactulose
(CAS: 4618-18-2)

Lactulose, a disaccharide composed of galactose and fructose, is a stimulator of health-promoting bacterium growth in the gastrointestinal tract, used to treat ...

BMS-955829
(CAS: 1375751-08-8)

BMS-955829 shows excellent Metabotropic glutamate receptor 5 (mGluR5) binding affinity, low glutamate fold shift, and high selectivity for the mGluR5 subtype. B...

FR-181074
(CAS: 184147-65-7)

FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction.

CAS 23180-57-6 Paeoniflorin

Paeoniflorin
(CAS: 23180-57-6)

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the pro...

CAS 1415379-56-4 T807

T807
(CAS: 1415379-56-4)

T807, also known as 18F-AV-1451, is a novel tau positron emission tomography (PET) tracer.

THK5351 R enantiomer

THK5351 R enantiomer is an R enantiomer of THK5351 which can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain and bou...

CAS 37921-38-3 Cimifugin

Cimifugin
(CAS: 37921-38-3)

Cimifugin is a major components of Yu-ping-feng-san, a Chinese medical formula that is used clinically for allergic diseases and characterized by reducing aller...

CAS 209467-52-7 Ceftobiprole

Ceftobiprole
(CAS: 209467-52-7)

Ceftobiprole is a cephalosporin prodrug with potent bactericidal activity against methicillin-resistant MRSA and penicillin-resistant Streptococcus pneumoniae (...

CAS 63223-86-9 Ginsenoside Rh1

Ginsenoside Rh1
(CAS: 63223-86-9)

Ginsenoside Rg1, the predominant ginsenoside in the rhizome,shows no hemolytic nor cytotoxic activities.It acts as a weak phytoestrogen, presumably by binding a...

Chemical Structure

CAS 106740-09-4 GYY-4137 Morpholine salt

Quick Inquiry

Verification code

Featured Items