|Description||GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, seems to be a candidate in the clinical management of colorectal tumors.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
ELN 484228 is an α-Synuclein blocker with activity in cellular models of α-synuclein-mediated dysfunction such as Parkinson’s Disease. Study showed that ELN4842...
IQ-R, a indolequinone derivative, could be used as a fluorescent probe.
MS 21570, a GPR171 antagonist (IC50 = 220 nM), inhibits BigLEN mediated increases in [35S]GTPγS binding in hypothalamic membranes and hyperpolarization of basol...
N-Cyclopropyl-N-methyl-2-Aminotetraline hydrobromide is a MAO inhibitor.
Paquinimod, also known as ABR‑215757, belonging to the class of quinoline-3-carboxamide derivatives, is a S100A9 inhibitor. Paquinimod is an immunomodulatory co...
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity o...
CGP 71683 hydrochloride
CGP 71683 hydrochloride is a highly selective non-peptide antagonist of the NPY Y(5) receptor (IC50= 1.4 nM) with > 1000-fold selectivity over Y1 (IC50= 2765 nM...
Terbuthylazine is a triazine herbicide.
Hydrastine, a natural alkaloid compound, could be used as a dopamine biosynthesis inhibitor.
Dixanthogen is the dominant species of xanthate adsorption on pyrite used as an ectoparasiticide.
Elobixibat is a potent and selective IBAT inhibitor under development for the treatment of chronic constipation and irritable bowel syndrome with constipation。
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.
Paritaprevir could inhibit viral phosphoprotein NS5A and is significant to viral replication and other activities. It also has been found to have potential effe...
MS 023 is a potent and selective type I PRMT inhibitor (IC50= 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Importantly, MS02...
3PO is originally reported to inhibit PFKFB3 (IC50 = 25 μM), with the potential to inhibit cancer cell proliferation. The addition of selective inhibitors of au...
Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, su...
Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.
Lalistat 1 is a lysosomal acid lipase inhibitor with IC50 value of 68 nM. It can block LAL-mediated lipid hydrolysis of acetylated LDL and reduce efflux of chol...
PFK15 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM.
Ridogrel is a thromboxane synthase inhibitor used for the prevention of systemic thrombo-embolism. It is also a receptor antagonist that may be used as an adjun...