GW791343 HCl - CAS 309712-73-0
Catalog number: 309712-73-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H27Cl3F2N4O
Molecular Weight:
483.81
COA:
Inquire
Targets:
P2X7
Description:
GW791343, as a P2X7 receptor antagonist, was a negative allosteric modulator of the human P2X(7) receptor but at the rat P2X(7) receptor its predominant effect was positive allosteric modulation
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Purity:
≥98%
Appearance:
White solid
Synonyms:
2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide;trihydrochloride
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
P2X7 receptor antagonist
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
WSBRAHWNJBXXJM-UHFFFAOYSA-N
InChI:
1S/C20H24F2N4O.3ClH/c1-14-2-3-15(13-26-8-6-23-7-9-26)10-19(14)25-20(27)12-24-16-4-5-17(21)18(22)11-16;;;/h2-5,10-11,23-24H,6-9,12-13H2,1H3,(H,25,27);3*1H
Canonical SMILES:
CC1=C(C=C(C=C1)CN2CCNCC2)NC(=O)CNC3=CC(=C(C=C3)F)F.Cl.Cl.Cl
Current Developer:
GlaxoSmithKline
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