LY364947 is a selective inhibitor of TGF-β type-I receptor with potential anticancer activity. LY364947 inhibits TGF-β-dependent luciferase production in mink l...
LSKL, Inhibitor of Thrombospondin (TSP-1), derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-β, thus prevents the p...
Galunisertib, also known as LY2157299, is a novel selective small molecule transforming growth factor beta receptor (TGF-βR) kinase inhibitor.LY2157299 inhibite...
SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII.
Repsox is an inhibitor of the TGF-β type 1 activin like kinase receptor ALK5. At 25 μM, it can be used to induce stem cell pluripotency by replacing the reprogr...
EW-7197 is a potent ALK5 inhibitor. EW-7197 showed potent in vivo anti-metastatic activity, indicating its potential for use as an anti-cancer therapy. EW-7197...
A-77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5( IC50 =25nM).
ITD-1 is an effective and highly selective TGF-β signaling inhibitor which could promote cardiomyocyte differentiation through degradation of the TGFBR2 so that...