GW-6604 - CAS 452342-37-9
Catalog number:
452342-37-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H14N4
Molecular Weight:
298.34
COA:
Inquire
Targets:
Others
Description:
GW6604 is a potent and selective ALK-5 inhibitor with an IC(50) of 140 nM and in a cellular assay inhibited TGF-beta-induced transcription of PAI-1 (IC(50): 500 nM). In vivo, GW6604 (40 mg kg(-1) p.o.) increased liver regeneration in TGF-beta-overexpressing mice, which had undergone partial hepatectomy.
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Purity:
≥98%
Appearance:
Solid powder
Synonyms:
2-phenyl-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
ALK-5 inhibitor
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
BDCBRQYHYNUWAM-UHFFFAOYSA-N
InChI:
1S/C19H14N4/c1-2-6-14(7-3-1)18-12-15(9-11-21-18)16-13-22-23-19(16)17-8-4-5-10-20-17/h1-13H,(H,22,23)
Canonical SMILES:
C1=CC=C(C=C1)C2=NC=CC(=C2)C3=C(NN=C3)C4=CC=CC=N4
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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Chemical Structure

CAS 452342-37-9 GW-6604

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