GW 441756 - CAS 504433-23-2
Catalog number:
504433-23-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C17H13N3O
Molecular Weight:
275.30
COA:
Inquire
Targets:
Trk Receptor
Description:
GW 441756 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor (IC50 = 2 nM), reducing cell proliferation and potentiates the effects of chemotherapeutic agents.
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Purity:
≥98%
Appearance:
Orange solid
Synonyms:
1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one; (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A specific Tropomyosin-related kinase A (TrkA) inhibitor
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
NXNQLECPAXXYTR-LCYFTJDESA-N
InChI:
1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
Canonical SMILES:
CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
Current Developer:
GlaxoSmithKline
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CAS 504433-23-2 GW 441756

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