GTPγS - CAS 94825-44-2
Category: Nucleotides
Molecular Formula:
C10H16N5O13P3S (free acid)
Molecular Weight:
539.24 (free acid)
COA:
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Structure\Application:
Phosphate modified Nucleotides | Nucleotides applied on Proteins/Enzymes
Description:
GTPγS is a stable G-protein-activating (GTP) analog. The physiological actions of GTPgammaS includestimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
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Purity:
≥ 90 % by HPLC, contains < 10 % GDP
Appearance:
solid
Synonyms:
Guanosine-5'-(γ-thio)-triphosphate, Tetralithium salt; Guanosine-5'-(3-thio)-triphosphate; Guanosine-5'-(3-thiotriphosphate)
MSDS:
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InChIKey:
XOFLBQFBSOEHOG-UHFFFAOYSA-N
InChI:
InChI=1S/C10H16N5O13P3S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-29(19,20)27-30(21,22)28-31(23,24)32/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H,21,22)(H2,23,24,32)(H3,11,13,14,18)
Canonical SMILES:
C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=S)(O)O)O)O)NC(=NC2=O)N
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