GSK583 - CAS 1346547-00-9
Catalog number:
1346547-00-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H19FN4O2S
Molecular Weight:
398.46
COA:
Inquire
Targets:
Ser/Thr Protease
Description:
GSK583 is a selective receptor-interacting serine/threonine-protein kinase 2 (RIP2 Kinase) inhibitor and the RIP2K binding IC50 is 5 nM. GSK583 can inhibit both TNF-α and IL-6 production with an IC50 value of 200 nM in an ex vivo human translational model.
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Purity:
98%
Appearance:
Powder
Synonyms:
6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine
Solubility:
DMSO ≥ 37 mg/mL
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Gram
InChIKey:
XLOGLWKOHPIJLV-UHFFFAOYSA-N
InChI:
1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
Canonical SMILES:
O=S(C1=CC=C(N=CC=C2NC3=NNC4=C3C=C(F)C=C4)C2=C1)(C(C)(C)C)=O
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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