|Description||GSK583 is a selective receptor-interacting serine/threonine-protein kinase 2 (RIP2 Kinase) inhibitor and the RIP2K binding IC50 is 5 nM. GSK583 can inhibit both TNF-α and IL-6 production with an IC50 value of 200 nM in an ex vivo human translational model.|
|Solubility||DMSO ≥ 37 mg/mL|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
BAY-1217389, an imidazopyridazin derivative, has been found to be a TTK protein inhibitor that could probably be effective as an antineoplastic agent and also b...
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A potent inhibitor of dipeptidyl peptidase IV (DPP-IV)
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