|Description||GSK 4112, a kind of synthetic agonist of REV-ERBα, could suppress the expression of sorts of genes involved in gluconeogenesis. IC50: 0.4 μM (EC50).|
|Solubility||10 mM in DMSO|
|Application||GSK 4112 is a kind of synthetic agonist of REV-ERBα and could suppress the expression of sorts of genes involved in gluconeogenesis.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors.
GAT-100, an indole derivative, has been found to be a negative allosteric modulator that could be used as a covalent probe in studying of the binding motifs of ...
Ridinilazole is a non-absorbable small molecule antibiotic for oral administration to treat Clostridium difficile infection (CDI), showed statistical superiorit...
NSC 663284 is a potent, irreversible, cell permeable and mixed competitive Cdc25 dual specificity phosphatases inhibitor (IC50= 0.21 μM), and poorly inhibits ot...
AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (...
Dixanthogen is the dominant species of xanthate adsorption on pyrite used as an ectoparasiticide.
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
This active molecular is a bio-active chemical but detailed information has not been published yet.
Sanguinarine chloride hydrate
Sanguinarine is a benzylisoquinoline alkaloid isolated from Papaveraceae with antimicrobial, anti-inflammatory, and anti-oxidant properties.
Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units with IC50 of 94 μM.
Importazole is a cell-permeable inhibitor of importin-β. Importazole specifically inhibits the function of importin-β, likely by altering its interaction with R...
Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and...
Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.
Dienestrol is a synthetic and non-steroidal estrogen, which structurally related to stilbestrol. It is an estrogen receptor agonist and a metabolite of Diethyls...
NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease.
Aurothioglucose is used in the treatment of rheumatoid arthritis and psoriasis.
Cgp 20309 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage.