GSK369796 Dihydrochloride - CAS 1010411-21-8
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H24Cl3N3O
Molecular Weight:
428.78
COA:
Inquire
Targets:
Antiparasitic
Description:
SK369796, also known as N-tert-butylisoquine, shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain. GSK369796 was rationally designed based on chemical, toxicological, pharmacokinetic, and pharmacodynamic considerations and was selected based on excellent activity against Plasmodium falciparum in vitro and rodent malaria parasites in vivo.
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Appearance:
Solid powder
Synonyms:
2-[(tert-Butylamino)methyl]-5-[(7-chloroquinolin-4-yl)amino]phenol Dihydrochloride; GSK369796 Dihydrochloride; GSK 369796; GSK-369796; GSK369796; N-tert-Butyl isoquine.
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
UDVALKJFXQVZSI-UHFFFAOYSA-N
InChI:
1S/C20H22ClN3O.2ClH/c1-20(2,3)23-12-13-4-6-15(11-19(13)25)24-17-8-9-22-18-10-14(21)5-7-16(17)18;;/h4-11,23,25H,12H2,1-3H3,(H,22,24);2*1H
Canonical SMILES:
OC1=CC(NC2=CC=NC3=CC(Cl)=CC=C23)=CC=C1CNC(C)(C)C.[H]Cl.[H]Cl
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CAS 1010411-21-8 GSK369796 Dihydrochloride

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