GSK369796 Dihydrochloride - CAS 1010411-21-8
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H24Cl3N3O
Molecular Weight:
428.78
COA:
Inquire
Targets:
Antiparasitic
Description:
SK369796, also known as N-tert-butylisoquine, shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain. GSK369796 was rationally designed based on chemical, toxicological, pharmacokinetic, and pharmacodynamic considerations and was selected based on excellent activity against Plasmodium falciparum in vitro and rodent malaria parasites in vivo.
Publictions citing BOC Sciences Products
  • >> More
Appearance:
Solid powder
Synonyms:
2-[(tert-Butylamino)methyl]-5-[(7-chloroquinolin-4-yl)amino]phenol Dihydrochloride; GSK369796 Dihydrochloride; GSK 369796; GSK-369796; GSK369796; N-tert-Butyl isoquine.
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
UDVALKJFXQVZSI-UHFFFAOYSA-N
InChI:
1S/C20H22ClN3O.2ClH/c1-20(2,3)23-12-13-4-6-15(11-19(13)25)24-17-8-9-22-18-10-14(21)5-7-16(17)18;;/h4-11,23,25H,12H2,1-3H3,(H,22,24);2*1H
Canonical SMILES:
OC1=CC(NC2=CC=NC3=CC(Cl)=CC=C23)=CC=C1CNC(C)(C)C.[H]Cl.[H]Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antiparasitic Products


CAS 26002-80-2 Phenothrin

Phenothrin
(CAS: 26002-80-2)

Phenothrin, also called as Forte or Sumithrin, a synthetic pyrethroid, is an antiparasitic drug that is used to kills adult fleas and ticks.

CAS 23110-15-8 Fumagillin

Fumagillin
(CAS: 23110-15-8)

Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagil...

CAS 3736-81-0 Diloxanide furoate

Diloxanide furoate
(CAS: 3736-81-0)

Diloxanide furoate is an ambecide used to treat infection with amoebas.

CAS 551-92-8 Dimetridazole

Dimetridazole
(CAS: 551-92-8)

Dimetridazole is a nitroimidazole-based compound that combats protozoan infections, with antibacterial and anticoccidial activity

CAS 7175-09-9 Tilbroquinol

Tilbroquinol
(CAS: 7175-09-9)

Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has been used against Vibrio cholerae.

CAS 100-33-4 Pentamidine

Pentamidine
(CAS: 100-33-4)

Pentamidine is an antimicrobial agent.

CAS 6119-47-7 Quinine hydrochloride dihydrate

Quinine hydrochloride dihydrate
(CAS: 6119-47-7)

Quinine Hydrochloride Dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflamm...

CAS 1491-41-4 Naftalofos

Naftalofos
(CAS: 1491-41-4)

Naftalofos, an isoquinolin derivative, has been found to be an insecticide and commonly used in sheep.

CAS 50357-45-4 Pentamidine

Pentamidine
(CAS: 50357-45-4)

Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein. It is an antimicrobial medication given for prevention and ...

CAS 185055-67-8 Ferroquine

Ferroquine
(CAS: 185055-67-8)

Ferroquine, a ferrocene-based analogue, is an ingenious antimalarial agent potentially for the treatment of malaria.

CAS 55268-74-1 Praziquantel

Praziquantel
(CAS: 55268-74-1)

Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective aga...

CAS 133413-70-4 PF 1022A

PF 1022A
(CAS: 133413-70-4)

The cyclic depsipeptide PF1022A showed very good anthelmintic activity against Heligmosomoides polygyrus and Heterakis spumosa at 50 mg/kg. In vitro, PF1022A wa...

CAS 69004-04-2 Toltrazuril sulfone

Toltrazuril sulfone
(CAS: 69004-04-2)

Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites. It, sold by the Bayer Corporation under the trade name Marquis, is a drug curre...

CAS 58-14-0 Pyrimethamine

Pyrimethamine
(CAS: 58-14-0)

Pyrimethamine is a medication used for protozoal infections. It could interfere with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dih...

CAS 6506-37-2 Nimorazole

Nimorazole
(CAS: 6506-37-2)

Nimorazole is a nitroimidazole anti-infective. It significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be...

CAS 74847-35-1 Pyronaridine

Pyronaridine
(CAS: 74847-35-1)

Pyronaridine is an antimalarial drug. Pyronaridine was first synthesized in 1970 and has been in clinical use in China since the 1980s. It is one of the compone...

CAS 3818-50-6 Bephenium hydroxynaphthoate

Bephenium hydroxynaphthoate
(CAS: 3818-50-6)

Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis, which belongs to B-type AChR activato...

CAS 33401-94-4 Pyrantel tartrate

Pyrantel tartrate
(CAS: 33401-94-4)

Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock. Pyrantel tartrate salt is used to study a...

CAS 7681-76-7 Ronidazole

Ronidazole
(CAS: 7681-76-7)

Ronidazole is an antiprotozoal agent.

CAS 71963-77-4 Artemether

Artemether
(CAS: 71963-77-4)

Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

Chemical Structure

CAS 1010411-21-8 GSK369796 Dihydrochloride

Quick Inquiry

Verification code

Featured Items