|Description||SK369796, also known as N-tert-butylisoquine, shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain. GSK369796 was rationally designed based on chemical, toxicological, pharmacokinetic, and pharmacodynamic considerations and was selected based on excellent activity against Plasmodium falciparum in vitro and rodent malaria parasites in vivo.|
|Synonyms||2-[(tert-Butylamino)methyl]-5-[(7-chloroquinolin-4-yl)amino]phenol Dihydrochloride; GSK369796 Dihydrochloride; GSK 369796; GSK-369796; GSK369796; N-tert-Butyl isoquine.|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
PPA-904 is a specific phenothiazine photosensitizer that reached a phase II trial in patients with chronic venous Leg ulcer but was subsequently discontinued.
Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites. It, sold by the Bayer Corporation under the trade name Marquis, is a drug curre...
Spirodiclofen, a tetronic acid derivative, is a broad spectrum acaricide.
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.
Phenothrin, also called as Forte or Sumithrin, a synthetic pyrethroid, is an antiparasitic drug that is used to kills adult fleas and ticks.
Diclazuril is an anti-coccidial drug.
Bithionol is a clinically approved anti-parasitic drug. It has been shown to inhibit solid tumor growth in several preclinical cancer models. It caused dose dep...
Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms, which is a veteran anthelm...
Cefoxitin is is derived from cephamycin C, a semi-synthetic, broad-spectrum cepha antibiotic often grouped with the second-generation cephalosporins.
Ferroquine, a ferrocene-based analogue, is an ingenious antimalarial agent potentially for the treatment of malaria.
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. It is a promising compound for the therapy and prophylaxis of a...
Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity.
Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has been used against Vibrio cholerae.
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective aga...
Niclosamide Monohydrate is used for the treatment of most tapeworm infections by inhibiting DNA replication. It inhibits the TNF-induced NF-κB reporter activity...
Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis, which belongs to B-type AChR activato...
Pyronaridine tetraphosphate is an antimalarial agent with an inhibitory effect on P-glycoprotein mediated drug resistance. It inhibits B-hematin formation and E...
Dimetridazole is a nitroimidazole-based compound that combats protozoan infections, with antibacterial and anticoccidial activity
Pyrimethamine is a medication used for protozoal infections. It could interfere with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dih...