GSK2837808A - CAS 1445879-21-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31H25F2N5O7S
Molecular Weight:
649.62
COA:
Inquire
Targets:
Others
Description:
GSK2837808A is a potent and specific lactate dehydrogenase A (LDHA) with IC50values of 1.9 and 14 nM for LDHA and LDHB, respectively and inhibits lactate production in selected cancer cell lines.
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Brife Description:
A potent and selective lactate dehydrogenase A (LDHA) inhibitor
Synonyms:
3-[[3-(cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino]-5-(3,5-difluorophenoxy)benzoic acid
Solubility:
DMSO: ≥100 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
783.5±70.0 ℃ at 760 Torr
Density:
1.57±0.1 g/cm3
InChIKey:
RZBCPMYJIARMGV-UHFFFAOYSA-N
InChI:
1S/C31H25F2N5O7S/c1-43-29-25(14-35-31(37-29)44-2)16-3-6-24-26(9-16)34-15-27(46(41,42)38-20-4-5-20)28(24)36-21-7-17(30(39)40)8-22(13-21)45-23-11-18(32)10-19(33)12-23/h3,6-15,20,38H,4-5H2,1-2H3,(H,34,36)(H,39,40)
Canonical SMILES:
COC1=NC(=NC=C1C2=CC3=NC=C(C(=C3C=C2)NC4=CC(=CC(=C4)C(=O)O)OC5=CC(=CC(=C5)F)F)S(=O)(=O)NC6CC6)OC
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CAS 1445879-21-9 GSK2837808A

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