GSK2606414 - CAS 1337531-36-8
Catalog number:
1337531-36-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Targets:
PERK
Description:
GSK2606414 is an orally available, potent, and selective PERK inhibitor. GSK2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small molecule inhibitors.
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Purity:
0.98
Appearance:
white solid powder
Synonyms:
GSK2606414; GSK-2606414; GSK 2606414
MSDS:
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CAS 1337531-36-8 GSK2606414

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