|Description||GSK-2330672, an ASBT inhibitor, has been developed for the treatment of type 2 diabetes and is currently under Phase II trail against primary biliary cirrhosis and type 2 diabetes. IC50: 42 ± 3 nM.|
|Synonyms||CHEMBL2387408; UNII-386012Z45S; GSK2330672; GSK-2330672; SCHEMBL2586025; CZGVOBIGEBDYTP-VSGBNLITSA-N|
|Solubility||DMSO: ≥ 21.5 mg/mL|
|Application||GSK-2330672 is an ASBT inhibitor that has been developed for the treatment of type 2 diabetes and is currently under Phase II trail against primary biliary cirrhosis and type 2 diabetes.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
Dextrose, a simple sugar (monosaccharide), is an important carbohydrate in biology.
This molecular is a piperidine derivative with an amine protecting group. It may be used in the preparation of biologically active compounds like selective irre...
GSK-2330672, an ASBT inhibitor, has been developed for the treatment of type 2 diabetes and is currently under Phase II trail against primary biliary cirrhosis ...
4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine. It is a nonpolar, essential amino acid that naturally occurs in the human body and is als...
LDN-27219 is a revesible inhibitor of transglutaminase 2 (TG2) that binds to the GTP binidng site of the enzyme and inhbits activity with and IC50 of 600 nM.
Glyparamide is a chlorophenyl-containing sulfonylurea with hypoglycemic activity and rarely causes hepatic injury.
The sodium salt form of Disufenton, a benzenesulfonate compound, has been found to be a free radical scavenger that was once studied in acute ischaemic stroke t...
LY-195448 is a phenethanolamine. It blocks cells at metaphase. It has shown anti-tumour activity.
Desmopressin acetate, also know as DDAVP, has been found to be a vasopressor agent that could exhibit antidiuretic activity and probably be useful in improving ...
Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibites apoptosis, and blocks nonenzymatic peroxidation and lipoxygen...
Sulfabenzamide is a widely used intermediate in many chemical areas and has been found to have antibacterial activity.
Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-dis...
Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.
TAK-243, a pyrazolopyrimidine derivative, has been found to be an Ubiquitin-protein ligase inhibitor and was just finished the Phase-I trial against solid tumou...
Trichloromethane is a solvent, as a powerful blister agent used for chemical warfare.
Evans Blue is a potent inhibitor of L-glutamate uptake into synaptic vesicles and is able to antagonize AMPA (IC50=220 nM) and kainate receptor (IC50=150 nM) me...
Lubabegron is a β3-adrenoreceptor agonist.
Ginsenoside Rc, a sort of triterpene saponin, is extracted from ginseng and has been found to be antioxidative, anti-aging and has sorts of other properties. It...
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the pro...
Prim-O-glucosylcimifugin is a natural product extracted from the root of Saposhnikovia divaricata (Turcz.) Schischk. It can inhibit the proliferation of SMC(smo...