GSK2194069 - CAS 1332331-08-4
Catalog number:
1332331-08-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H24N4O3
Molecular Weight:
428.48
COA:
Inquire
Targets:
Others
Description:
GSK2194069 is a fatty acid synthase (FAS) inhibitor. GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ± 4.1 nM for the overall hFAS reaction. FAS is upregulated in some cancers, including prostate cancer. GSK2194069 was found to inhibit tumour growth in prostate cancer C42b cell xenografts generated in Nod-SCID-gamma mice. Cellular FAS inhibition reduced cell growth were also demonstrated in non-small-cell lung (A549) cancer cell lines with an average EC50 of 15 ± 0.5 nM.
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Purity:
>98%
Synonyms:
GSK 2194069; GSK-2194069
MSDS:
Inquire
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1332331-08-4 GSK2194069

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