GSK215083 - CAS 607742-80-3
Catalog number:
607742-80-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H20FN3O2S
Molecular Weight:
385.46
COA:
Inquire
Targets:
5-HT Receptor
Description:
GSK215083 is a PET radioligand for the 5-hydroxytrypamine-6 (5HT6) receptor. It is a quinoline based compounds that acts by antagonising the 5-HT6 receptor. It binds to receptors 5HT6 in the striatum and 5-hydroxytryptamine-2A (5HT2A) in the frontal cortex. It is used for the treatment of Alzheimer's disease and used as a PET ligand for identification of occupancy of the 5HT6 receptor coupled with 11C.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
3-(3-Fluoro-benzenesulfonyl)-8-(4-Methyl-piperazin-1-yl)-quinoline;GSK-215083;Quinoline, 3-((3-fluorophenyl)sulfonyl)-8-(4-methyl-1-piperazinyl)-
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
GSK215083 is used for the treatment of Alzheimer's disease and used as a PET ligand for identification of occupancy of the 5HT6 receptor coupled with 11C.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Boiling Point:
585.8±50.0 °C | Condition: Press: 760 Torr
Density:
1.317±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
XVIUHTAVQLTUGA-UHFFFAOYSA-N
InChI:
InChI=1S/C20H20FN3O2S/c1-23-10-12-24(13-11-23)18-7-3-6-17-19(8-9-22-20(17)18)27(25,26)16-5-2-4-15(21)14-16/h2-9,14H,10-13H2,1H3
Canonical SMILES:
CN1CCN(CC1)C2=CC=CC3=C(C=CN=C32)S(=O)(=O)C4=CC=CC(=C4)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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