|Description||GSK215083 is a PET radioligand for the 5-hydroxytrypamine-6 (5HT6) receptor. It is a quinoline based compounds that acts by antagonising the 5-HT6 receptor. It binds to receptors 5HT6 in the striatum and 5-hydroxytryptamine-2A (5HT2A) in the frontal cortex. It is used for the treatment of Alzheimer's disease and used as a PET ligand for identification of occupancy of the 5HT6 receptor coupled with 11C.|
|Solubility||Soluble in DMSO, not in water|
|Application||GSK215083 is used for the treatment of Alzheimer's disease and used as a PET ligand for identification of occupancy of the 5HT6 receptor coupled with 11C.|
|Quality Standard||In-house standard|
|Boiling Point||585.8±50.0 °C | Condition: Press: 760 Torr|
|Density||1.317±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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