GSK-J2 - CAS 1394854-52-4
Catalog number:
1394854-52-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H23N5O2
Molecular Weight:
389.45
COA:
Inquire
Targets:
Histone Demethylase
Description:
GSK-J2, a benzazepin derivative, has been found to have poor activity as a JMJD3 inhibitor so that could be used in the biological study of GSK-J1 as a negative control. IC50: > 100 μM.
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Purity:
98%
Appearance:
Powder
Synonyms:
SK-J2; GSK J2; 1394854-52-4; SCHEMBL15937902; 3705AH
Solubility:
DMSO: ≥ 42 mg/mL
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
GSK-J2 has been found to have poor activity as a JMJD3 inhibitor so that could be used in the biological study of GSK-J1 as a negative control.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Millgrams-Grams
InChIKey:
LJIFOCRGDDQFJF-UHFFFAOYSA-N
InChI:
InChI=1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,26)
Canonical SMILES:
C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CN=CC=C4)NCCC(=O)O
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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