GSK 9027 - CAS 1229096-88-1
Category: Inhibitor
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Molecular Formula:
C27H19F4N3O2S
Molecular Weight:
525.52
COA:
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Targets:
Glucocorticoid Receptor
Description:
GSK 9027 is a glucocorticoid receptor agonist (pIC50 = 8) inhibiting production of the proinflammatory mediator IL-6 in vivo. GSK 9027 is used for the treatment of acute and chronic inflammatory conditions.
Brife Description:
glucocorticoid receptor agonist
Purity:
≥98% by HPLC
Synonyms:
GSK 9027; GSK9027; GSK-9027; N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
MSDS:
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InChIKey:
DXBJGDVBQPEMOB-UHFFFAOYSA-N
InChI:
InChI=1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
Canonical SMILES:
C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
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CAS 1229096-88-1 GSK 9027

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