GSK'872 - CAS 1346546-69-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H17N3O2S2
Molecular Weight:
383.49
COA:
Inquire
Targets:
RIP kinase
Description:
GSK'872 is aRIPK3inhibitor, which binds RIP3 kinase domain with high affinity (IC50=1.8 nM), and is approximately >1,000-fold selective over 300 kinases in a fluorescence polarization assay at a concentration of 1 μM. Besides, GSK'872 inhibits kinase activity (IC50=1.3 nM).
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Brife Description:
An inhibitor of receptor interacting protein kinase-3 (RIP3)
Synonyms:
N-(6-propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine
Solubility:
DMSO: ≥ 150 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
625.7±55.0 ℃ at 760 Torr
Density:
1.395±0.06 g/cm3
InChIKey:
ZCDBTQNFAPKACC-UHFFFAOYSA-N
InChI:
1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22)
Canonical SMILES:
CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4
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CAS 1346546-69-7 GSK'872

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