GSK-7975A - CAS 1253186-56-9
Catalog number: 1253186-56-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H12F5N3O2
Molecular Weight:
397.31
COA:
Inquire
Targets:
Others
Description:
This active molecular is a calcium release-activated calcium modulator (ORAI1) inhibitor. GSK-7975A inhibited toxin-induced activation of ORAI1 and/or activation of Ca(2+) currents after Ca(2+) release in mouse and human pancreatic acinar cells. GSK-7975A may be used for the treatment of pancreatitis in the future.
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Purity:
98%
Appearance:
Powder
Synonyms:
SCHEMBL705705; AOB4124; CPYTVBALBFSXSH-UHFFFAOYSA-N;2,6-difluoro-N-[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
pancreatitis
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
CPYTVBALBFSXSH-UHFFFAOYSA-N
InChI:
InChI=1S/C18H12F5N3O2/c19-13-2-1-3-14(20)16(13)17(28)24-15-6-7-26(25-15)9-10-4-5-11(27)8-12(10)18(21,22)23/h1-8,27H,9H2,(H,24,25,28)
Canonical SMILES:
C1=CC(=C(C(=C1)F)C(=O)NC2=NN(C=C2)CC3=C(C=C(C=C3)O)C(F)(F)F)F
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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