| Molecular Formula: | |
|---|---|
| Molecular Formula | C18H12F5N3O2 |
| Molecular Weight: | |
| Molecular Weight | 397.31 |
| COA: | |
| COA | Inquire |
| Targets: | |
| Targets | Others |
| Description: | |
| Description | This active molecular is a calcium release-activated calcium modulator (ORAI1) inhibitor. GSK-7975A inhibited toxin-induced activation of ORAI1 and/or activation of Ca(2+) currents after Ca(2+) release in mouse and human pancreatic acinar cells. GSK-7975A may be used for the treatment of pancreatitis in the future. |
| Purity: | |
|---|---|
| Purity | 98% |
| Appearance: | |
| Appearance | Powder |
| Synonyms: | |
| Synonyms | SCHEMBL705705; AOB4124; CPYTVBALBFSXSH-UHFFFAOYSA-N;2,6-difluoro-N-[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide |
| Solubility: | |
| Solubility | Soluble in DMSO |
| Storage: | |
| Storage | -20°C Freezer |
| MSDS: | |
| MSDS | Inquire |
| Application: | |
| Application | pancreatitis |
| Quality Standard: | |
| Quality Standard | In-house standard |
| Shelf Life: | |
| Shelf Life | 2 month in rt, long time |
| Quantity: | |
|---|---|
| Quantity | Milligrams-Grams |
| InChIKey: | |
| InChIKey | CPYTVBALBFSXSH-UHFFFAOYSA-N |
| InChI: | |
| InChI | InChI=1S/C18H12F5N3O2/c19-13-2-1-3-14(20)16(13)17(28)24-15-6-7-26(25-15)9-10-4-5-11(27)8-12(10)18(21,22)23/h1-8,27H,9H2,(H,24,25,28) |
| Canonical SMILES: | |
| Canonical SMILES | C1=CC(=C(C(=C1)F)C(=O)NC2=NN(C=C2)CC3=C(C=C(C=C3)O)C(F)(F)F)F |
| Current Developer: | |
| Current Developer | GSK |
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