|Description||This active molecular is a calcium release-activated calcium modulator (ORAI1) inhibitor. GSK-7975A inhibited toxin-induced activation of ORAI1 and/or activation of Ca(2+) currents after Ca(2+) release in mouse and human pancreatic acinar cells. GSK-7975A may be used for the treatment of pancreatitis in the future.|
|Synonyms||SCHEMBL705705; AOB4124; CPYTVBALBFSXSH-UHFFFAOYSA-N;2,6-difluoro-N-[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
Guanoxyfen sulfate is an inhibitor of vasoconstrictor responses to sympathetic nerve stimulation. It could potentiate the actions of adrenaline and noradrenalin...
(±)-Lauroylcarnitine chloride is an acylcarnitine used to improve in vivo absorption of certain hydrophilic compounds.
Butylhydroxyanisole, also called as AMIF 72, Nipantiox 1 F or Butyl Methoxyphenol, with antioxidative property it is used as a food additive preservative.
The phenotypic responses of sensitive plants exposed to amicarbazone include chlorosis, stunted growth, tissue necrosis, and death. Its efficacy as both a folia...
This molecular is a novel non-peptide tachykinin NK3 receptor antagonist and it has a very high affinity for native guinea pig (pK(i) value 7.8) tachykinin NK(3...
Dropropizine is a racemic non-opiate antitussive agent, it is used as a cough suppressant.Dropropizine exhibits antitussive activity in cats noticeably lower th...
Astragaloside IV has cardiovascular protective effects. It can protect the vascular endothelial cells. Meanwhile, it also have antiinflammatory and anti-virus e...
15(R)-17-phenyl trinor Prostaglandin F2α
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 ...
Tribromoethanol is a sedative. It is used to anesthetize laboratory animals, particularly rodents, prior to surgery. It has the brand name Avertin as a solution...
CTX-0294885 hydrochloride is the hydrochloride salt of CTX-0294885 which displays high affinity toward an extensive range of kinases. The evaluation of the bind...
Desmopressin acetate, also know as DDAVP, has been found to be a vasopressor agent that could exhibit antidiuretic activity and probably be useful in improving ...
Geneticin (G418 Sulfate)
Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.G418 is an inhibitor of many pro- and eukaryot...
Leflunomideinhibits the reproduction of rapidly dividing cells by inhbiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH).
Mechlorethamine is the prototype of alkylating agents, it works by binding to DNA, crosslinking two strands and preventing cell duplication.
17α-Hydroxy Progesterone, as a metabolite of Progesterone, is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid ho...
L-Thyroxine sodium salt pentahydrate
L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol l...
Difopein has been found to be a 14.3.3 protein inhibitor and could induce apoptosis expressed in COS-7 and some cancer cells.
PF 4693627 is a potent, selective and orally bioavailable inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) that has the potential to treat inflamma...
TC-S 7006 is a potent, selective and reversible Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM) with selectivity for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. TC-...
C-DIM12 is a novel synthetic activator of Nurr1. C-DIM12 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. .