GSK-356278 - CAS 720704-34-7
Catalog number: 720704-34-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H25N7O2S
Molecular Weight:
439.54
COA:
Inquire
Targets:
PDE4
Description:
GSK-356278 is a selective Type 4 cyclic nucleotide phosphodiesterase inhibitor. It shows anxiolytic and cognition-enhancing effects and it has the ability to elevate cAMP in various cell types of the central nervous system. No development was reported for phase-I development in Major depressive disorder and Huntington's-disease.
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Purity:
98%
Appearance:
Powder
Synonyms:
5-(5-((2,4-dimethyl-5-thiazolyl)methyl)-1,3,4-oxadiazol-2-yl)-1-ethyl-n-(tetrahydro-2H-pyran-4-yl)-1H-Pyrazolo(3,4-b)pyridin-4-amine
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
Huntington's disease; Major depressive disorder
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
AWDJJMXJUOHGLC-UHFFFAOYSA-N
InChI:
1S/C21H25N7O2S/c1-4-28-20-15(11-23-28)19(25-14-5-7-29-8-6-14)16(10-22-20)21-27-26-18(30-21)9-17-12(2)24-13(3)31-17/h10-11,14H,4-9H2,1-3H3,(H,22,25)
Canonical SMILES:
CCn1c2c(cn1)c(c(cn2)c3nnc(o3)Cc4c(nc(s4)C)C)NC5CCOCC5
Current Developer:
Originator GlaxoSmithKline
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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