|Molecular Formula||C26H28N6O • HCl|
|Description||GSK-2269557 is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by GlaxoSmithKline. GSK-2269557 is highly selective for PI3Kδ over the closely related isoforms and is active in a animal model of Th2-driven lung inflammation. Treatment for Asthma and Chronic obstructive pulmonary disease(COPD) is in clinical trials Phase II.|
|Synonyms||6-(1H-indol-4-yl)-4-[5-[[4-(1-methylethyl)-1-piperazinyl]methyl]-2-oxazolyl]-1H-indazole, monohydrochloride;1254036-71-9(free base)|
|Solubility||Soluble in DMSO|
|Application||Asthma; Chronic obstructive pulmonary disease|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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GSK-2269557 HCl salt
GSK-2269557 is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by GlaxoSmithKline. GSK-2269557 is highly selective for PI3Kδ over the close...
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