GSK-2269557 HCl salt - CAS 1254036-77-5
Catalog number:
1254036-77-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H28N6O • HCl
Molecular Weight:
477.01
COA:
Inquire
Targets:
PI3K
Description:
GSK-2269557 is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by GlaxoSmithKline. GSK-2269557 is highly selective for PI3Kδ over the closely related isoforms and is active in a animal model of Th2-driven lung inflammation. Treatment for Asthma and Chronic obstructive pulmonary disease(COPD) is in clinical trials Phase II.
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Purity:
98%
Appearance:
Powder
Synonyms:
6-​(1H-​indol-​4-​yl)​-​4-​[5-​[[4-​(1-​methylethyl)​-​1-​piperazinyl]​methyl]​-​2-​oxazolyl]​-1H-​indazole, monohydrochloride;1254036-71-9(free base)
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Asthma; Chronic obstructive pulmonary disease
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
MCIDWGZGWVSZMK-UHFFFAOYSA-N
InChI:
1S/C26H28N6O/c1-17(2)32-10-8-31(9-11-32)16-19-14-28-26(33-19)22-12-18(13-25-23(22)15-29-30-25)20-4-3-5-24-21(20)6-7-27-24/h3-7,12-15,17,27H,8-11,16H2,1-2H3,(H,29,30)
Canonical SMILES:
CC(C)N(CC1)CCN1CC2=CN=C(C3=C(C=NN4)C4=CC(C5=CC=CC6=C5C=CN6)=C3)O2
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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