|Description||GSK-1440115 is an orally active urotensin II receptor antagonist. It is used for the treatment of asthma.|
|Synonyms||GSK1440115;4'-(1-(((6,7-Dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl)(methyl)amino)-2-(4-morpholinyl)ethyl)-4-diphenylcarboxylic acid;4-[4-[(1R)-1-[[2-(6,7-dichloro-3-oxo-1,4-benzoxazin-4-yl)acetyl]-methylamino]-2-morpholin-4-ylethyl]phenyl]benzoic acid|
|Solubility||10 mM in DMSO|
|Application||GSK-1440115 is used for the treatment of asthma.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Melting Point||858.9±65.0 °C | Condition: Press: 760 Torr|
|Density||1.378±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
Benflumetol, also known as HSDB 7210, is an antimalarial drug used to treat acute uncomplicated malaria. It is used in combination with Artemether for improved ...
Methyl linolenate, a polyunsaturated fattly acid (PUFA), is an autoxidation product that is used to study the mechanisms and prevention of oxidation/peroxidatio...
Propylthiouracil is a thyroperoxidase and 5'-deiodinase inhibitor. It is a thiouracil-derived drug used to treat hyperthyroidism (including Graves' disease) by ...
CGP 3466B maleate
CGP 3466B maleate, a potent anti-apoptotic drug, is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. CGP 3466B maleate was tested in...
Penicillamine is used as an antirheumatic and as a chelating agent in Wilson’s disease.
FR-218944 is a vasopressin antagonist compound.
p53 and MDM2 proteins-interaction-inhibi
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins.
Clioxanide is an anthelmintic agent.
Ikarisoside F, a flavonol glycoside from Vancouveria hexandra, could bind to AdoHcy hydrolase.
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in...
Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake ...
MART-1 (26-35) human
MART-1 (26-35), an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein, is amino acid residue 26 to 35 of MART-1 protein.
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
9-Aminoacridine is a highly fluorescent dye, an acridine analog. It is used clinically as a topical antiseptic and experimentally as a mutagen. It is an intrace...
D-Mannitol inhibits renal tubular reabsorption of sodium, chloride, and other solutes.It also inhibits neutrophil apoptosis.
Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being develo...
Dithioerythritol, a sulfur containing sugar derived from the corresponding 4-carbon monosaccharide erythrose, is an epimer of dithiothreitol(DTT).
Meticrane, a sulphonamide derivative, is an effective diuretic and also an inhibitor of peripheral-type benzodiazepine receptor. IC50: 1 μM.
GYKI-13380is a bio-active compound. But no detailed information has been published ye