GSK-1268992 - CAS 1414375-49-7
Catalog number:
1414375-49-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H23N7O3S
Molecular Weight:
453.52
COA:
Inquire
Targets:
Others
Description:
GSK-1268992 is one of a metabolite of Pazopanib which is a selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
GSK 1268992; Pazopanib metabolite M24;5-((4-((3-(Hydroxymethyl)-2-methyl-indazol-6-yl)-methyl-amino)pyrimidin-2-yl)amino)-2-methyl-benzenesulfonamide
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
KRXYEFGZHAJXHW-UHFFFAOYSA-N
InChI:
1S/C21H23N7O3S/c1-13-4-5-14(10-19(13)32(22,30)31)24-21-23-9-8-20(25-21)27(2)15-6-7-16-17(11-15)26-28(3)18(16)12-29/h4-11,29H,12H2,1-3H3,(H2,22,30,31)(H,23,24,25)
Canonical SMILES:
Cc1ccc(cc1S(=O)(=O)N)Nc2nccc(n2)N(C)c3ccc4c(c3)nn(c4CO)C
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 119793-66-7 Propionyl-L-Carnitine HCl

Propionyl-L-Carnitine HCl
(CAS: 119793-66-7)

The hydrochloride salt form of L-Propionylcarnitine which has been found to be related to mitochondrial metabolism so that could be used in the treatment deteri...

CAS 28598-08-5 Cinoctramide

Cinoctramide
(CAS: 28598-08-5)

Cinoctramide is an intermediate of pharmaceutical synthesis.

CAS 137-58-6 Lidocaine

Lidocaine
(CAS: 137-58-6)

Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

PD-116152
(CAS: 101708-64-9)

PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp.

CMPD101
(CAS: 865608-11-3)

CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DA...

CAS 383907-43-5 NSC 663284

NSC 663284
(CAS: 383907-43-5)

NSC 663284 is a potent, irreversible, cell permeable and mixed competitive Cdc25 dual specificity phosphatases inhibitor (IC50= 0.21 μM), and poorly inhibits ot...

CAS 133-67-5 Trichlormethiazide

Trichlormethiazide
(CAS: 133-67-5)

Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.

CAS 54048-10-1 Etonogestrel

Etonogestrel
(CAS: 54048-10-1)

A impurity of Desogestrel, which is a progestogen.

CAS 80573-04-2 Balsalazide

Balsalazide
(CAS: 80573-04-2)

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is a new 5-aminosalicylic acid (5-ASA) containing prodrug. It i...

CC-17369
(CAS: 1547162-46-8)

CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.

CAS 81-23-2 Dehydrocholic Acid

Dehydrocholic Acid
(CAS: 81-23-2)

Dehydrocholic Acid is a derivative of Cholic Acid and manufactured by the oxidation of cholic acid. It is produced by choleretic and isolated from liver cells. ...

CAS 84272-85-5 4-O-beta-D-gulcosyl-5-O-methylvisamminol

4-O-beta-D-gulcosyl-5-O-methylvisamminol
(CAS: 84272-85-5)

4-O-β-D-Glucosyl-5-O-methyllvisamminol is a natural product isolated from the roots of Saposhnikovia divaricata (Turcz.) Schischk. It is a novel epigenetic supp...

CAS 637-58-1 Pramoxine HCl

Pramoxine HCl
(CAS: 637-58-1)

Pramoxine is a topical local anesthetic that has been shown to have antipruritic properties.Like other local anesthetics, paramoxine decreases the permeability ...

LBM-415
(CAS: 478913-91-6)

LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, was tested by reference methods against 2 collections of pathogenic Neisseria being developed for c...

pGlu-Pro-Arg-MNA
(CAS: 130835-45-9)

pGlu-Pro-Arg-MNA is a peptide compound that has potential biology activity in many areas.

CAS 551-11-1 Dinoprost

Dinoprost
(CAS: 551-11-1)

Dinoprost is a widely distributed PG occurring in many species,causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exh...

CAS 155294-62-5 NB-598 Maleate

NB-598 Maleate
(CAS: 155294-62-5)

SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibit...

CAS 100557-06-0 AR12456

AR12456
(CAS: 100557-06-0)

AR12456 is a trapidil derivative. It could protect against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a choles...

CAS 41708-72-9 ToCainide

ToCainide
(CAS: 41708-72-9)

Tocainide, a lidocaine analog, is a class Ib antiarrhythmic agent.

CAS 66952-49-6 Methasulfocarb

Methasulfocarb
(CAS: 66952-49-6)

Methasulfocarb is a fungicide compound.

Quick Inquiry

Verification code

Featured Items