GSK-1071306 - CAS 1252927-47-1
Catalog number: 1252927-47-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H21N7O2S
Molecular Weight:
423.49
COA:
Inquire
Targets:
Others
Description:
GSK-1071306 is one of the metabolites of pazopanib which is a inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity as a approved drug.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
Pazopanib metabolite M27;5-((4-((2,3-dimethyl-2H-indazol-6-yl)amino)-2-pyrimidinyl)amino)-2-methyl-Benzenesulfonamide
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
XWOGXAVHJKKNPO-UHFFFAOYSA-N
InChI:
1S/C20H21N7O2S/c1-12-4-5-15(11-18(12)30(21,28)29)24-20-22-9-8-19(25-20)23-14-6-7-16-13(2)27(3)26-17(16)10-14/h4-11H,1-3H3,(H2,21,28,29)(H2,22,23,24,25)
Canonical SMILES:
Cc1ccc(cc1S(=O)(=O)N)Nc2nccc(n2)Nc3ccc4c(n(nc4c3)C)C
Current Developer:
GSK
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


Nanterinone mesylate
(CAS: 102791-74-2)

Nanterinone mesylate is the methyl sulfonate form of Nanterinone, which is a novel positive inotropic and balanced-type vasodilating drug partially based on pho...

CAS 130693-82-2 Dorzolamide hydrochloride

Dorzolamide hydrochloride
(CAS: 130693-82-2)

Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide hydrochlor...

Monohydroxy Netupitant
(CAS: 910808-12-7)

Monohydroxy Netupitant is the metabolite of Netupitant which is a potent and selective neurokinin-1 receptor (NK1) receptor antagonist. It is achiral and orally...

Ritobegron ethyl hydrochloride
(CAS: 476333-91-2)

Ritobegron is a potential Bladder selectivity of the novel β₃-agonist.

CAS 632-85-9 Wogonin

Wogonin
(CAS: 632-85-9)

Wogonin is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.

CAS 23674-86-4 Difluprednate

Difluprednate
(CAS: 23674-86-4)

Difluprednate (difluoroprednisolone butyrate acetate, or DFBA) is a synthetic difluorinated prednisolone derivative, it is originally developed for dermatologic...

SR9011
(CAS: 1379686-29-9)

SR9011, a synthetic REV-ERB agonist, has been found to have probable effect against sleep disorders and metabolic diseases. IC50: 790 nM and 560 nM for Rev-ErbB...

KHK-IN-1
(CAS: 1303469-70-6)

KHK-IN-1, a pyrimidinopyrimidine derivative, is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in ...

CAS 52286-59-6 Ginsenoside Re

Ginsenoside Re
(CAS: 52286-59-6)

Ginsenoside Re, extracted from the traditional Chinese herb ginseng, responsible for some of the pharmacological functions.

CAS 288-32-4 Imidazole

Imidazole
(CAS: 288-32-4)

Imidazole, a highly polar compound, has been used extensively as a corrosion inhibitor and a buffer in the pH range of 6.2-7.8.

Hexa-His

Hexa-His, consisting of 6 His residues in a row, called His-Tag, is used as a metal binding site for the recombinant protein. His-Tag sequence can be placed on ...

CAS 470-37-1 Cinobufagin

Cinobufagin
(CAS: 470-37-1)

Cinobufagin can inhibit the proliferation of U-2OS cells, and induce cell apoptosis. The potential mechanism of Cinobufagin-induced apoptosis may be related to ...

CAS 1216897-16-3 2-(5-fluoropentyl)-2-methylmalonic acid

2-(5-fluoropentyl)-2-methylmalonic acid
(CAS: 1216897-16-3)

This molecular is a [18F] PET (positron emission tomography) radiotracer. It can accumulate in cells presenting apoptosis-specific membrane alterations. ML-10 a...

CAS 147493-44-5 Pyridazinediones-derivative-1

Pyridazinediones-derivative-1
(CAS: 147493-44-5)

It inhibits glutamate-induced contractions of isolated guineapig ileum (ED50= 2.1 μM) with potential to treat neurodegenerative disorders.

CAS 1223397-11-2 WZB 117

WZB 117
(CAS: 1223397-11-2)

WZB 117 is a GLUT inhibitor (Ki(app) = 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively) that inhibits passive glucose transport in human erythrocytes...

CAS 75921-69-6 Melanotan I

Melanotan I
(CAS: 75921-69-6)

A synthetic analogue of α-melanocyte stimulating hormone (α-MSH)

CAS 1184-16-3 NADP monosodium salt

NADP monosodium salt
(CAS: 1184-16-3)

Sodium Salt Hydrate form of NADP which is a coenzyme widely exist in living organism and commonly related to oxidation-reduction reactions.

CAS 877963-94-5 LOC14

LOC14
(CAS: 877963-94-5)

LOC14 is a protein disulfide isomerase modulator with Kd value of 62 nM. It can force protein disulfide isomerase to adopt an oxidized conformation and suppress...

CAS 471-95-4 Bufotalin

Bufotalin
(CAS: 471-95-4)

Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species. It is a novel anti-osteoblastoma agent.

CAS 1255517-77-1 UNC 0638

UNC 0638
(CAS: 1255517-77-1)

UNC 0638 is a selective inhibitor of G9a/EHMT2 and GLP histone lysine methyltransferases (IC50 values are < 15 nM and 19 nM for G9a and GLP respectively, and > ...

Quick Inquiry

Verification code

Featured Items