Grapiprant (CJ-023423) - CAS 415903-37-6
Catalog number: B0084-470919
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H29N5O3S
Molecular Weight:
491.61
COA:
Inquire
Targets:
Prostaglandin Receptor
Description:
Grapiprant, also known as CJ-023,423, RQ-00000007 and AAT-007, is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-470919 10 mg $198 In stock
Bulk Inquiry
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Solid powder
Synonyms:
CJ-023423; CJ 023423; CJ023423; CAS#415903-37-6; RQ-00000007; RQ 00000007; RQ00000007; AAT-007; AAT007; AAT 007; Grapiprant
Solubility:
Soluble in DMSO, not in water
Storage:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years if stored properly
Canonical SMILES:
O=C(NCCC1=CC=C(C=C1)N2C(CC)=NC3=C(N=C(C=C32)C)C)NS(C4=CC=C(C=C4)C)(=O)=O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Prostaglandin Receptor Products


CAS 571170-77-9 Laropiprant

Laropiprant
(CAS: 571170-77-9)

Laropiprant is a potent, selective DP1 receptor antagonist (Ki=0.57 nM) used in combination with niacin to reduce blood cholesterol (LDL and VLDL).

CAS 1175526-27-8 AM-211

AM-211
(CAS: 1175526-27-8)

This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary dis...

CAS 847728-01-2 CJ-42794

CJ-42794
(CAS: 847728-01-2)

CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist. It inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It ...

CAS 915191-42-3 MF498

MF498
(CAS: 915191-42-3)

MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, a Gs protein-coupled receptor, with Ki of 0.7 nM. It plays important roles in ...

CAS 892549-43-8 Mf-63

Mf-63
(CAS: 892549-43-8)

Mf-63 is a selective Microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Its IC50 value is 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, r...

CAS 39746-25-3 16,16-Dimethyl Prostaglandin E2

16,16-Dimethyl Prostaglandin E2
(CAS: 39746-25-3)

16,16-Dimethyl Prostaglandin E2, a prostaglandin E2 derivative, could induce an increase in hematopoietic stem cell (HSC) numbers in mouse model.

CAS 72814-32-5 BW 245C

BW 245C
(CAS: 72814-32-5)

BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1)agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding ...

FR-181157
(CAS: 200433-03-0)

FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor.

CAS 2624-44-4 Ethamsylate

Ethamsylate
(CAS: 2624-44-4)

Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhe...

CAS 55028-72-3 Cloprostenol sodium

Cloprostenol sodium
(CAS: 55028-72-3)

Cloprostenol sodium is a synthetic and water-soluble aryl-oxymethyl analog of prostaglandin F2α. lt is also a potent inhibitor of rat adipose precursor differen...

GSK-345931A sodium
(CAS: 869499-38-7)

GSK-345931A is an EP(1) receptor antagonist. It is efficient in preclinical models of inflammatory pain.

ONO 8711 dicyclohexyl amine salt

ONO 8711 dicyclohexyl amine salt is a selective and competitive prostaglandin E (PGE) receptor EP1 antagonist with chemopreventive activity. It suppresses tumor...

CAS 439288-66-1 GW 627368X

GW 627368X
(CAS: 439288-66-1)

GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity (Ki values of 100 nM and 158 nM, resp...

CAS 155206-00-1 Bimatoprost

Bimatoprost
(CAS: 155206-00-1)

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

CAS 58551-69-2 Carboprost tromethamine

Carboprost tromethamine
(CAS: 58551-69-2)

Carboprost tromethamine is the salt of Carboprost, an analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha). Carboprost activates prostaglandin F ...

Fevipiprant
(CAS: 872365-14-5)

Fevipipran is a reversible competitive CRTh2 antagonist with IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. ...

MF592
(CAS: 1064195-48-7)

MF592 is a potent and selective antagonists of the EP4 receptor. It has good functional potency and potent inhibition of PGE2 modulated TNFa release in LPS stim...

CAS 143443-90-7 Ifetroban

Ifetroban
(CAS: 143443-90-7)

Ifetroban is a selective Prostaglandin receptor and Thromboxane A2 receptor antagonist under the development of Bristol-Myers Squibb. Phase II clinical trials f...

CAS 59122-46-2 Misoprostol

Misoprostol
(CAS: 59122-46-2)

Misoprostol, a synthetic analog of natural prostaglandin E1, is an effective anti-ulcer agent and also has oxytocic properties.

CAS 1369489-71-3 E7046

E7046
(CAS: 1369489-71-3)

E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities.

Chemical Structure

CAS 415903-37-6 Grapiprant (CJ-023423)

Quick Inquiry

Verification code

Featured Items