Gramine - CAS 87-52-5
Catalog number: 87-52-5
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C11H14N2
Molecular Weight:
174.24
COA:
Inquire
Description:
Gramine, a naturally occurring indole alkaloid, is a 5-HT2A antagonist.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
MSDS:
Inquire
1.Removal of Two Species of Harmful Algae Using Gramine Modified Montmorillonite.
Liu SL1, Wang WW1,2, Liu F1, Li HY1, Liu JS1, Yang WD3. Bull Environ Contam Toxicol. 2016 Apr;96(4):540-3. doi: 10.1007/s00128-016-1758-y. Epub 2016 Feb 27.
A series of gramine modified montmorillonites (gramine-MMTs) were prepared and characterized by thermogravimetric analysis, X-ray diffraction and zeta potential measurements. These modified clays with various amounts of gramine all exhibited higher removal efficiencies of both Chattonella marina and Alexandrium tamarense than did natural clay. With the augmentation of gramine content in the modified clays, the removal efficiency increased. The 24 h LC50 values of gramine-MMT with 12.68 % of gramine on C. marina and A. tamarense were 9.16 and 10.21 mg L(-1), respectively. These data suggest gramine-MMT might be a promising material to remediate harmful algal blooms.
2.Natural xenobiotics to prevent cyanobacterial and algal growth in freshwater: contrasting efficacy of tannic acid, gallic acid, and gramine.
Laue P1, Bährs H2, Chakrabarti S3, Steinberg CE4. Chemosphere. 2014 Jun;104:212-20. doi: 10.1016/j.chemosphere.2013.11.029. Epub 2013 Dec 13.
Allelochemical action against planktonic phototrophs is one central issue in freshwater ecology and quality management. To determine some basic mechanisms of this toxic action, we exposed the coccal green alga, Desmodesmus armatus, and the coccal cyanobacterium, Microcystis aeruginosa, in a batch culture well-supplied with carbon dioxide to increasing concentrations of the polyphenols tannic acid and gallic acid and the alkaloid gramine. The phototrophs were checked after 2d and at the end of the culture for biomass-based growth rates, cell volume, maximum quantum yield of photosystem II (ΦPSIImax), chlorophyll a content (chla) after 2d and at the end of the culture, and lipid peroxidation only at the end of the culture. During the culture, the pH rose from 7.64 to 10.95, a pH characteristic of eutrophic freshwater bodies during nuisance algal blooms. All xenobiotics reduced the growth rate, ΦPSIImax, and chla during the first 2d with M.
3.Removal of Two Species of Harmful Algae Using Gramine Modified Montmorillonite.
Liu SL1, Wang WW1,2, Liu F1, Li HY1, Liu JS1, Yang WD3. Bull Environ Contam Toxicol. 2016 Apr;96(4):540-3. doi: 10.1007/s00128-016-1758-y. Epub 2016 Feb 27.
A series of gramine modified montmorillonites (gramine-MMTs) were prepared and characterized by thermogravimetric analysis, X-ray diffraction and zeta potential measurements. These modified clays with various amounts of gramine all exhibited higher removal efficiencies of both Chattonella marina and Alexandrium tamarense than did natural clay. With the augmentation of gramine content in the modified clays, the removal efficiency increased. The 24 h LC50 values of gramine-MMT with 12.68 % of gramine on C. marina and A. tamarense were 9.16 and 10.21 mg L(-1), respectively. These data suggest gramine-MMT might be a promising material to remediate harmful algal blooms.
4.Strategies for the Total Synthesis of Clavicipitic Acid.
Ito M1, Tahara YK1, Shibata T2,3. Chemistry. 2016 Apr 11;22(16):5468-77. doi: 10.1002/chem.201505014. Epub 2016 Jan 28.
Clavicipitic acid is an ergot alkaloid, which was isolated from Claviceps strain and Claviceps fusiformis. Its unique tricyclic azepinoindole skeleton has attracted synthetic chemists, and various strategies have been developed for its total synthesis. These strategies can be generally categorized into two types based on the synthetic intermediates, namely, 4-substituted gramine derivatives and 4-substituted tryptophan derivatives. This Minireview summarizes the reported total syntheses from the point of these two key intermediates.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Chemical Structure

CAS 87-52-5 Gramine

Quick Inquiry

Verification code

Featured Items